年龄相关性黄斑变性与甲状腺疾病的关系

M. Abdelkader, N. Abass
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引用次数: 3

摘要

本研究的目的是评估促甲状腺激素(TSH)、游离三碘甲状腺原氨酸(T3)、游离甲状腺素(T4)、甲状腺功能减退、甲状腺功能亢进和年龄相关性黄斑变性(ARMD)发病率之间的关系。在2014年1月至2019年2月期间,共有950名甲状腺疾病患者和530名非甲状腺患者参与了这项研究。测量血压、血糖、胆固醇、吸烟状况。测定TSH、t3、t4。视网膜摄影和光学相干断层扫描。甲亢患者ARMD发生率增高。使用甲状腺素的患者的ARMD发生率也高于未使用甲状腺素的患者。甲状腺功能障碍合并ARMD患者的婚姻、文化程度、吸烟比例均高于甲状腺功能正常者(p=0.03)。0.06, 0.001)。在甲状腺疾病患者中,有无ARMD患者在糖尿病、高血压和胆固醇水平上的差异有统计学意义(p分别为0.04、0.09、0.03)。我们得出结论,在甲亢和使用甲状腺素的患者中,ARMD的发生率都有所增加。
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The Relation Between Age Related Macular Degeneration and Thyroid Disorders
The Purpose of the study was to evaluate the association between thyroid -stimulating hormone (TSH), free tri-iodothyronine (T3), free thyroxine (T4), hypothyroidism, hyperthyroidism and age related macular degeneration (ARMD) incidence. Nine hundred and fifty patients with thyroid disorders versus five hundred and thirty eu-thyroid subjects were included in the study during the period from January 2014 to February 2019. Blood pressure, blood sugar level and cholesterol, smoking state were estimated. TSH, T3&T4 were measured. Retinal photography and optical coherence tomography were performed. Patients with hyperthyroidism had increased incidence of ARMD. Patients using thyroxine had also increased incidence of ARMD than non using of thyroxine. There were statistically higher significant percent of marriage, educational level and smoking in patients with thyroid disorders with ARMD than euthyroid (p=0.03. 0.06, 0.001 respectively). In thyroid disorders patients, there were a significant differences between patients had ARMD or had not as regard diabetes, hypertension and cholesterol level (p=0.04, 0.09, 0.03 respectively). We concluded that there were increased incidence of ARMD in both hyperthyroidism, and patients use the thyroxine.
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