安全、简单的肾脏替代疗法治疗心脏手术后急性期伴有左心功能不全的血液透析患者:考虑右心参数作为预负荷指标

H. Ohno
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引用次数: 0

摘要

【背景】持续血液滤过(CHDF)具有实现血流动力学稳定的优势,但24(cid:514)小时透析存在各种问题,如患者约束、医务人员教育、人员和高医疗费用等问题。我们研究了用CHDF将透析时间从24小时缩短到8小时的效果。[方法]将术前左室射血分数<55%的患者20例(cid:514例)分为常规血液滤过组(H组)和CHDF 8 H血液滤过组(L组)。使用右心室射血导管,我们研究了透析期间发生的右心室容积等右心脏参数的变化。[结果]相对于干重的水分去除量较大,右心室末舒张容积(cid:514)下降率较小,l组血压降低率低于20%,肌酐和钾水平略高,但在可接受范围内。【结论】心脏手术后连续3天进行8小时CHDF(cid:514)为基础的血液滤过,可以在牺牲透析效率的情况下安全、充分地清除液体和溶液。在像我们这样中等规模的医院,这项技术可以作为常规血液透析的一个简单而有用的桥梁。
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Safe and simple renal replacement therapy for hemodialysis patients with left ventricular dysfunction in the acute phase after cardiac surgery: Consideration of right heart parameters as preloading indices
[Background] Continuous hemodiafiltration (CHDF) has the advantage of achieving hemodynamic stability, but 24(cid:514)hour dialysis is associated with various problems, such as problems relating to patient restraint, medical staff education, personnel, and high medical costs. We investigated the effects of shortening the duration of dialysis from 24 hours to 8 hours by using CHDF. [Method] Twenty(cid:514)three patients with preoperative left ventricular ejection fractions of <55% were divided into usual hemodiafiltration (group H) and 8 hoursʼ hemodiafiltration using CHDF (group L) groups. Using a right ventricular ejection catheter, we studied the changes in right heart parameters, such as right ventricular volume, that occurred during dialysis. [Results] Water removal relative to dry weight was larger, the rate of decline in right ventricular end(cid:514)diastolic volume was smaller, and the rate of reductions in blood pressure of ≥ 20% was lower in group L. Creatinine and potassium levels were slightly higher, but within acceptable limits, in group L. [Conclusions] Performing 8 hours of CHDF(cid:514)based hemodiafiltration for 3 consecutive days after cardiac surgery enabled safe and sufficient removal of fluids and solution at the expense of dialysis efficiency. This technique may be employed as a simple and useful bridge to routine hemodialysis in medium(cid:514)sized hospitals like ours.
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