Torque Teno病毒与肝炎:相关性研究进展

Siti Nurzulaikha Hazanudin, Zulkefley Othman, Z. Sekawi, C. Y. Kqueen, Rasnaizam Rasdi
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引用次数: 3

摘要

Torque teno病毒(TTV)是近20年前发现的“孤儿”病毒之一,关于感染与任何疾病的关系的信息很少。它是在人群中发现的45%的共生病毒之一,成为研究最广泛的病毒之一,研究其在不同健康状况水平中的流行程度。从健康的献血者到患有严重疾病的患者,TTV感染水平似乎很高,这一发现引起了研究人员的兴趣。尽管对TTV患病率的研究正在积极进行,但TTV对任何特定疾病的实际发病机制尚未确定。许多关于TTV感染与严重疾病(如急性呼吸道疾病、肝脏相关疾病甚至癌症)可能存在关联的建议已被讨论。然而,一种可能与TTV有关的疾病是肝炎。尽管如此,它仍然是一个理论,因为TTV的实际致病性尚不完全清楚。
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Torque Teno Virus and Hepatitis: A review on correlation.
Torque teno virus (TTV) is one of the “orphan” virus that have been discovered almost two decades ago, with little information on the relationship of the infection to any diseases. It is one of the 45% of commensal virus which was found throughout the population and becoming one of the most extensively studied viruses on its prevalence among various level of health status. From healthy blood donors to patients who suffered severe illness, TTV infection level seems to be high and the findings has triggered an interest from the researcher. Even though the study on TTV prevalence is actively performed, the actual pathogenesis of TTV to any specific diseases is yet to be ascertained. Many suggestions on the possible association of TTV infection with severe diseases such as acute respiratory diseases, liver-related diseases and even cancer have been discussed. However, one type of diseases which might have an association with TTV is hepatitis. Albeit, it remains a theory as the actual pathogenicity of TTV is not fully understood.
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