门静脉高压症:目前的外科治疗

L. Wancata, Christopher R. Connelly, S. Orloff
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引用次数: 0

摘要

门静脉高压症是由肝脏及其循环的多种疾病引起的。它被定义为门静脉循环和体循环之间的压力梯度升高。门静脉高压的主要临床后果是腹水和门静脉曲张的发展,这可能导致危及生命的出血。门静脉高压的现代治疗包括药物治疗、内窥镜治疗和介入放射学经颈静脉肝内门静脉系统分流术。历史上,门静脉高压症是通过外科门静脉系统分流治疗的。在本章中,将讨论门静脉高压症的生理学和治疗方法。具体来说,本章将重点介绍用于治疗门静脉高压症的手术分流的适应症、技术考虑和类型,以及支持这些手术的文献。三个案例报告描述最近成功的外科分流创建将提出。尽管随着医学、内窥镜和放射学干预措施的改进,门静脉系统外科分流术的实施频率大大降低,但本章表明,门静脉系统外科分流术是治疗门静脉高压症的重要工具。
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Portal Hypertension: Current Surgical Management
Portal hypertension occurs due to multiple disorders of the liver and its circulation. It is defined as an elevated pressure gradient between the portal circulation and the systemic circulation. The primary clinical consequences of portal hypertension are ascites and the development of portosystemic varices, which may cause life threatening hemorrhage. Modern management of portal hypertension includes medical, endoscopic therapy and transjugular intrahepatic portosystemic shunt placement by interventional radiology. Historically, portal hypertension was treated through the creation of surgical portosystemic shunts. In this chapter, the physiology of portal hypertension and the approaches to its management will be discussed. Specifically, the chapter will focus on indications, technical considerations, and types of surgical shunts used to treat portal hypertension, as well as literature supporting these procedures. Three case reports describing recent successful surgical shunt creation will be presented. Although portosystemic surgical shunt creation is performed far less frequently as medical, endoscopic and radiologic interventions have improved, this chapter illustrates that this procedure is a vital tool to be used in the treatment of portal hypertension.
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