紧急开始腹膜透析的实施减少了非计划开始透析患者血液透析导管的使用和住院时间

F. Artunc, Sandra Rueb, K. Thiel, C. Thiel, K. Linder, Dorothea Baumann, H. Bunz, Thomas Muehlbacher, M. Mahling, M. Sayer, Marlies Petsch, M. Guthoff, N. Heyne
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引用次数: 9

摘要

背景:肾脏替代治疗在终末期肾病患者中很常见,通常通过使用中心静脉导管(CVC)进行血液透析(HD)来完成。紧急开始使用腹膜透析(PD)可能是一些患者的另一种选择;然而,这需要一个以医院为基础的PD中心,提供结构化的紧急启动PD (usPD)计划。方法:在这项前瞻性研究中,我们描述了在我们大学医院实施usPD计划的过程,从提出到PD导管植入和PD在几天内开始。为了临床验证,我们比较了usPD可用前(2013-2015年)和可用后(2016-2018年)的患者流量。结果:在usPD可用前的3年里,14% (n = 12)的PD患者(n = 87)出现在计划外的情况下,最初使用CVC治疗HD。在实施usPD计划的3年后,18% (n = 18)的PD患者(n = 103)出现意外情况,其中n = 12(12%)接受了usPD治疗,n = 6(6%)接受了初始HD治疗。usPD显著减少了57%的HD使用(p = 0.0005)。与选择性PD患者(8天)相比,usPD患者(中位9天)的住院时间相似,且显著低于初始HD患者(26天,p = 0.0056)。结论:usPD方案的实施减少了HD导管的使用和意外情况下的住院时间。
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Implementation of Urgent Start Peritoneal Dialysis Reduces Hemodialysis Catheter Use and Hospital Stay in Patients with Unplanned Dialysis Start
Background: Unplanned start of renal replacement therapy is common in patients with end-stage renal disease and often accomplished by hemodialysis (HD) using a central venous catheter (CVC). Urgent start using peritoneal dialysis (PD) could be an alternative for some of the patients; however, this requires a hospital-based PD center that offers a structured urgent start PD (usPD) program. Methods: In this prospective study, we describe the implementation of an usPD program at our university hospital by structuring the process from presentation to PD catheter implantation and start of PD within a few days. For clinical validation, we compared the patient flow before (2013–2015) and after (2016–2018) availability of usPD. Results: In the 3 years before the availability of usPD, 14% (n = 12) of incident PD patients (n = 87) presented in an unplanned situation and were initially treated with HD using a CVC. In the 3 years after implementation of the usPD program, 18% (n = 18) of all incident PD patients (n = 103) presented in an unplanned situation of whom n = 12 (12%) were treated with usPD and n = 6 (6%) with initial HD. usPD significantly reduced the use of HD by 57% (p = 0.0005). Hospital stay was similar in patients treated with usPD (median 9 days) compared to those with elective PD (8 days), and significantly lower than in patients with initial HD (26 days, p = 0.0056). Conclusions: Implementation of an usPD program reduces HD catheter use and hospital stay in the unplanned situation.
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