强力霉素抗肿瘤活性谱的研究

Bo Chen, Honggang Zhou, Wei Wang, Wen-guang Gu, Dong Zhao, Peng-Lai Wang
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引用次数: 4

摘要

本研究通过体外(21种细胞系)和体内(4种荷瘤小鼠模型)实验来确定强力霉素的抗癌作用。该药物对肿瘤细胞有较强的抑制作用,可改善小鼠的生存状况。本研究还初步探讨了强力霉素对不同类型肿瘤细胞的抑制作用。
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Studies on antitumor activity spectrum of doxycycline
In this study, in vitro (21 kinds of cell lines) and in vivo (four kinds of tumor-bearing mouse models) experiments were performedto determine the anticancer effect of doxycycline. This drug may elicit a strong inhibitory effect on cancer cells and improve thesurvival condition of mice. This study also preliminarily investigated the inhibitory effect of doxycycline on different kinds oftumor cells.
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