{"title":"壳聚糖基支架材料及其在伤口愈合中的应用","authors":"Shakeel Ahmed , Saiqa Ikram","doi":"10.1016/j.als.2016.04.001","DOIUrl":null,"url":null,"abstract":"<div><p>Over the last decade, much interest has been developed in biopolymer based materials due to their biocompatible, biodegradable, non-toxic and non-allergenic nature. Chitosan is a unique biopolymer that exhibits outstanding properties, besides biocompatibility and biodegradability. Most of these peculiar properties arise from the presence of primary amines along the chitosan backbone. Many works have been done to obtain chitosan based scaffolds, including surface modifications, the fabrication of chitosan based blends, chitosan based composite scaffolds, and drug-loaded scaffolds. This study provides an overview of the key features of inherent properties of chitosan, their modification, and its use in biomedical engineering particularly toward anti-inflammatory and wound healing.</p></div>","PeriodicalId":100012,"journal":{"name":"Achievements in the Life Sciences","volume":"10 1","pages":"Pages 27-37"},"PeriodicalIF":0.0000,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.als.2016.04.001","citationCount":"391","resultStr":"{\"title\":\"Chitosan Based Scaffolds and Their Applications in Wound Healing\",\"authors\":\"Shakeel Ahmed , Saiqa Ikram\",\"doi\":\"10.1016/j.als.2016.04.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Over the last decade, much interest has been developed in biopolymer based materials due to their biocompatible, biodegradable, non-toxic and non-allergenic nature. Chitosan is a unique biopolymer that exhibits outstanding properties, besides biocompatibility and biodegradability. Most of these peculiar properties arise from the presence of primary amines along the chitosan backbone. Many works have been done to obtain chitosan based scaffolds, including surface modifications, the fabrication of chitosan based blends, chitosan based composite scaffolds, and drug-loaded scaffolds. This study provides an overview of the key features of inherent properties of chitosan, their modification, and its use in biomedical engineering particularly toward anti-inflammatory and wound healing.</p></div>\",\"PeriodicalId\":100012,\"journal\":{\"name\":\"Achievements in the Life Sciences\",\"volume\":\"10 1\",\"pages\":\"Pages 27-37\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.als.2016.04.001\",\"citationCount\":\"391\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Achievements in the Life Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2078152015300298\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Achievements in the Life Sciences","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2078152015300298","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Chitosan Based Scaffolds and Their Applications in Wound Healing
Over the last decade, much interest has been developed in biopolymer based materials due to their biocompatible, biodegradable, non-toxic and non-allergenic nature. Chitosan is a unique biopolymer that exhibits outstanding properties, besides biocompatibility and biodegradability. Most of these peculiar properties arise from the presence of primary amines along the chitosan backbone. Many works have been done to obtain chitosan based scaffolds, including surface modifications, the fabrication of chitosan based blends, chitosan based composite scaffolds, and drug-loaded scaffolds. This study provides an overview of the key features of inherent properties of chitosan, their modification, and its use in biomedical engineering particularly toward anti-inflammatory and wound healing.