土耳其多中心研究:COVID-19大流行期间与大流行前肾细胞癌手术的比较

Abdullah Gürel, B. Baylan, A. Özen, I. Keles, Ünal Öztekin, A. Demirbaş, Mustafa Karalar, K. Ulusoy, M. Yılmaz, E. Erşekerci, B. Elmaağaç, Hasan Sulhan, A. Doğan, M. Altan, M. Keske, M. Karadağ
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摘要

目的:2019冠状病毒病(COVID-19)大流行改变了卫生领域的各项重点。肾细胞癌(RCC)的许多选择性手术已被推迟。我们研究了2019冠状病毒病大流行对土耳其RCC手术治疗的影响。材料和方法:回顾性分析2019年3月1日至2021年2月28日土耳其9个中心手术治疗的457例肾肿瘤患者。结果:与疫情前同期相比,2019冠状病毒病大流行期间RCC手术治疗次数明显减少。两期入院症状相似(p=0.32)。然而,尽管没有统计学意义,但与大流行前相比,大流行期间因血尿住院率更高(分别为14.4%和9.8%)。两个研究期间术前影像学检测的转移性RCC率差异显著(分别为13.1%和6.1%,分别为COVID-19和COVID-19前)(p=0.01)。此外,研究时间从成像到手术的时间差异显著[分别为35(2-240)天和30(1-210)天,分别为COVID-19期间和COVID-19前期](p=0.01)。但两期肿瘤大小、手术类型、病理分期相似(p>=0.05)。尽管各组间病理分期相似,但大流行期因转移性疾病而行肾切除术的发生率显著高于对照组(p=0.01)。结论:大流行期间,rcc相关手术数量明显减少。然而,转移性疾病的手术率显著增加。©版权所有2022由泌尿肿瘤协会泌尿肿瘤公报/ Galenos Yayinevi 119出版。
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Comparison of Renal Cell Cancer Surgery During the COVID-19 Pandemic with Prepandemic Period, Turkey Multicenter Study
Objective: Coronavirus disease-2019 (COVID-19) pandemic changed various priorities in health area. Many elective surgeries for renal cell cancers (RCC) have been postponed. We examined the influence of the COVID-19 pandemic on the surgical treatment of RCC in Turkey. Material(s) and Method(s): Surgically treated 457 patients for kidney tumor, from March 1, 2019 to February 28, 2021 in 9 centers in Turkey were analyzed retrospectively. Result(s): The number of surgical treatments for RCC during the COVID-19 pandemic has decreased significantly, in contrast to the same period before COVID-19. Admission symptoms were similar in these two periods (p=0.32). However, although not statistically significant, the rate of admission to hospital due to hematuria was higher during the pandemic period compared to the prepandemic period (14.4% vs 9.8%, respectively). The two study periods differed significantly in terms of the rate of metastatic RCC detected in preoperative imaging (13.1% vs 6.1%, during COVID-19 and pre-COVID-19, respectively) (p=0.01). Moreover, the study periods differed significantly in terms of time between imaging and operation [35 (2-240) vs 30 (1-210) days, during COVID-19 and pre-COVID-19, respectively] (p=0.01). However, these two periods were similar in terms of tumor size, type of surgery, and pathological stage (p>=0.05). Although the pathological stages were similar among the groups, nephrectomies due to the metastatic disease were significantly higher in the pandemic period (p=0.01). Conclusion(s): The number of RCC-related surgeries were significantly decreased during the pandemic period. However, the rate of surgery for metastatic disease has significantly increased. © Copyright 2022 by Urooncology Association Bulletin of Urooncology / Published by Galenos Yayinevi 119.
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