肺炎球菌结合疫苗(PCV)对被遗忘的儿童杀手肺炎的影响

Nitin Shah
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引用次数: 2

摘要

肺炎球菌导致了近50%的严重肺炎病例和肺炎死亡。本文综述了肺炎球菌疫苗PCV7、PCV10和PCV13对社区获得性肺炎(CAP)的影响。在一些国家,PCV13的CAP减少量似乎比PCV10好得多。然而,将任何一种疫苗纳入发展中国家的国家免疫规划,都有可能挽救30万至50万人的死亡和700万至800万例严重的CAP。
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Impact of pneumococcal conjugate vaccines (PCV) on pneumonia, the forgotten killer of children

Pneumococcus contributes to nearly 50% of severe cases of pneumonia and pneumonia deaths. This article presents a literature review of the impact of the pneumococcal vaccines namely PCV7, PCV10 and PCV13 on community acquired pneumonia (CAP). It appears that the quantum of reduction of CAP is much better with PCV13 than PCV10 in several countries. However, inclusion of either vaccine in the national immunisation programme in developing countries has the potential to save 0.3–0.5 million deaths and 7–8 million episodes of severe CAP.

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