SiO2 Coating-Modified Magnetic Lidocaine as a Catalyst for the Synthesis of Quinazolin-4-ones, Benzo[d]thiazoles, and Benzo[d]imidazoles

A new composite was fabricated via the covalent grafting of magnetic lidocaine–Cu complex on silica support. The novelty of this composite is being magnetic and nontoxic. It was characterized by various techniques including FT-IR, X-ray diffraction (XRD), FE-SEM, EDX-map, and VSM. The applicability of this composite as a catalyst in the synthesis of quinazolin-4-ones, benzo[d]thiazoles, and benzo[d]imidazoles were investigated. The catalyst is advantageous owing to its drug base, environmental friendliness, high efficiency, cheapness, easy separation due to being magnetic, and the possibility of being reused four times.