在流行地区,肺叶切除术是治疗结节性甲状腺肿的合适手术策略吗?

Nurdan Altan
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摘要

简介:甲状腺结节是根据其放射学特征通过细针穿刺活检(FNAB)评估的。国际指南建议根据结节的大小和FNAB结果进行肺叶切除术。本研究的目的是评估肺叶切除术是否为流行地区的治疗选择之一。方法:回顾性分析2013年1月至2017年9月接受肺叶切除术的患者。记录患者的人口统计学特征、甲状腺激素水平、用药情况、术前FNAB结果、肺叶切除指征、超声特征、最终病理及二次手术干预。结果:对388例肺叶切除术患者的资料进行了分析。根据FNAB结果对患者进行分类,在最终病理结果中,所有类别的恶性肿瘤发生率均高于预期。118例(30.4%)患者行完全性甲状腺切除术。完成甲状腺切除术样本的最终病理显示24.07% (n=26)为恶性肿瘤。讨论与结论:FNAB是所有指南中判断甲状腺结节恶性风险的金标准。在流行地区,这种分类系统可能不够。两阶段甲状腺手术正变得越来越流行。在我们的研究中,根据最终病理结果,30.4%的患者接受了完全甲状腺切除术。我们需要在流行地区的指南中增加更新的内容。
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Is lobectomy an appropriate surgical strategy for nodular goiter in endemic areas?
Introduction: Thyroid nodules are evaluated by fine-needle aspiration biopsy (FNAB) according to their radiologic characteristics. International guidelines recommend lobectomy according to the size of the nodules and FNAB results. The aim of this study is to assess whether lobectomy is one of the treatment choices in endemic areas. Methods: Patients who underwent lobectomy between January 2013 and September 2017 were studied retrospectively. Patients’ demographic features, thyroid hormone levels, medications, FNAB results before the surgery, lobectomy indications, ultrasonographic features, final pathologies, and secondary surgical interventions were recorded. Results: Data of 388 patients who underwent lobectomy were examined. As patients were classified according to their FNAB results, all categories had higher malignancy rates than expected in the final pathology results. One hundred and eighteen (30.4%) patients had undergone completion thyroidectomy. The final pathology of the completion thyroidectomy samples showed 24.07% (n=26) malignancy. Discussion and Conclusion: FNAB is the gold standard for the malignancy risks in thyroid nodules in all guidelines. In endemic areas, this classification system may be inadequate. Two-staged thyroid surgery is becoming more popular. In our series, 30.4% of patients had undergone completion thyroidectomy according to their final pathology results. We need to add newer sights to guidelines for endemic areas.
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