高压下离子通道的实验

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology Pub Date : 2002-03-25 DOI:10.1016/S0167-4838(01)00359-4

Alister G. Macdonald

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引用次数: 14

摘要

离子通道是一种独特的膜蛋白，它为离子的扩散提供了一条门控途径。高压(< 100mpa)影响门控动力学，但不影响通道的电导。到目前为止，高压下通道的动态结构研究明显缺乏，但在单通道水平上使用膜片钳技术研究了功能特性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Experiments on ion channels at high pressure

Ion channels are distinctive membrane proteins which provide a gated pathway for diffusing ions. High pressure (<100 MPa) affects the kinetics of gating but not the conductance of the channel. Dynamic structural studies of channels at high pressure are, thus far, conspicuously absent but functional properties are studied at the single channel level with the patch clamp technique.

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Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

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