粒状封锁作为印度喀拉拉邦疫情控制策略的有效性

Hariprasad Thazhathedath Hariharan, A. T. Surendran
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引用次数: 0

摘要

封锁是一种久经考验的阻止传染病传播的方法。国家和地方一级的封锁有效地减少了COVID-19在包括印度在内的许多国家的传播。本文从印度南部喀拉拉邦的最低行政单位地方自治政府(LSG)这一更细致的层面记录了封锁的有效性。方法我们从喀拉拉邦政府的官方数据源中提取与本研究有关的所有数据:隔离区的分布和COVID-19病例的发病率。作为研究的一部分,我们在10周的研究期间(7/5/2020-15/7/2020)跟踪了所有LSGs作为隔离区的进展。我们创建了生存分布,描述了所有地区和州进入封锁的时间和保持封锁的时间。最后,我们对LSG控制期结束后6个月内每个人口的COVID-19累积发病率进行了区际比较,以确定其有效性。结果与喀拉拉邦其他地区相比,喀拉拉邦北部4个区在成为隔离区的LSGs比例和封锁期间都实施了更严格的封锁战略。结果,在研究期间,这4个区COVID-19病例的增长(7.5倍)低于其他区(37倍)。然而,疾病发病率的降低并不是瞬间的;与此同时,这种差异并不是短暂的,在封锁之后的6个多月里,这种差异仍然存在。结论实施细粒度封锁策略,只有在足够的范围内、适当的时间内,才能有效控制疾病的传播。我们相信,我们的研究可以帮助各国政府深入了解与这一流行病长达数年、永无止境的斗争。
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Effectiveness of Granular Lockdown as an Epidemic Control Strategy in Kerala, India
Background Lockdown is a time-tested methodology to cease infectious disease spread. The national and subnational lockdown effectively reduced the spread of COVID-19 in many countries, including India. The current article documents the effectiveness of lockdown at a more granular level, that is, the local self-government (LSG), the lowest administrative unit, in Kerala, a south Indian state. Methods We extracted all data pertaining to this study: the distribution of containment zones and the incidence of COVID-19 cases from official data sources of the Government of Kerala. As part of the study, we followed the progression of all LSGs as containment zones over the study period of 10 weeks (7/5/2020-15/7/2020). We created survival distributions characterizing the time to enter lockdown and the time to remain in lockdown for all the districts and the state. Finally, we conducted an interdistrict comparison of the cumulative incidence of COVID-19 per population for 6 months after the period of LSG containment was over to ascertain its effectiveness. Results Four northern districts of Kerala state had implemented lockdown strategy more rigorously both in the proportion of LSGs that has become a containment zone and in the period of containment compared to the rest of Kerala. As a result, the growth of COVID-19 cases in these 4 districts was less (7.5 times) than in the other districts (37 times) during the study period. However, the reduction in the disease incidence was not instantaneous; at the same time, it was not short-living as the difference continued to exist for 6 more months past lockdown. Conclusion Implementing granular lockdown strategies can effectively control the spread of disease only if it encompasses a sufficient area for an adequate period. We believe our research could help governments provide insights into the years-long and never-ending battle with the pandemic.
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期刊介绍: Indian Association of Clinical Medicine is an academic body constituted in the year 1992 by a group of clinicians with the main aim of reaffirming the importance of clinical medicine in this era of high-tech diagnostic modalities. There is no doubt that modern investigational methods have contributed a lot to the present day medical practice but that does not render clinical acumen and examination less important. The art and science of clinical medicine helps up to make proper and judicious use of investigations and not these be the sole basis of our practice. That is the basic idea behind this ''Association''. We presently have members and fellows of the association from all over the country. In August, 2002 the body was registered as "Indian Association of Clinical Medicine" by the Registrar of Societies, Delhi.
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