艾滋病毒感染者的COVID-19疫苗偏好和COVID-19风险与正常人群不同吗?

IF 0.3 4区 医学 Q4 Medicine Acta Medica Mediterranea Pub Date : 2022-06-13 DOI:10.32552/2022.actamedica.730
Ç. M. Ayaz, A. Baştuğ
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摘要

目的:2019冠状病毒病(COVID-19)可能在高危患者中有严重病程,人类免疫缺陷病毒(HIV, PLWH)感染者也在这一危险人群中。本研究的目的是比较PLWH与正常人群的COVID-19病史、疫苗接种状况、疫苗剂量和疫苗偏好。材料与方法:本研究为回顾性横断面调查研究。以PLWH患者为研究组,无慢性疾病患者为对照组。结果:共纳入326例患者,其中HIV阳性163例,无慢性疾病163例。其中男性142例(88.1%),平均年龄46.69±13.72岁。未接种疫苗的患者为36例(11.1%)。当评估未接种疫苗的PLWH时,观察到女性接种疫苗的人数少于男性患者(p=0.01)。在PLWH,单次接种145例(89.0%),双次接种129例(79.1%),全次接种123例(75.5%);对照组单剂量组145例(89.0%)、双剂量组131例(80.9%)、全剂量组126例(77.3%)接种疫苗。两组间对灭活疫苗和mRNA疫苗的偏好无差异(p=1.0)。接种前感染42例(12.9%)。PLWH组20例(12.3%),对照组22例(13.5%)。接种期间或接种后感染新冠肺炎28例(9.8%),其中PLWH组10例(6.9%);对照组18例(12.4%)。结论:在我们的研究中,两组在疫苗接种状况、疫苗偏好、疫苗接种剂量和COVID-19病史方面没有差异。
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Are COVID-19 Vaccine Preference and COVID-19 Risk Differ In Individuals Living with HIV from The Normal Population?
Objectives: Coronavirus disease 2019 (COVID-19) may have a severe course in high-risk patients and people living with Human immunodeficiency virus (HIV, PLWH)) are also in this risk group. The aim of the study was to compare the history of COVID-19, vaccination status, vaccine doses, and vaccine preferences of PLWH with the normal population.Materials and Methods: This study was a retrospective cross-sectional survey study. The PLWH were study group and patients without chronic disease were selected as a control group.Results: A total of 326 patients, 163 HIV positive and 163 without chronic disease, were included in the study. Of the patients, 142 (88.1%) were male, and the mean age was 46.69 ± 13.72 years. The number of patients who were not vaccinated was 36 (11.1%). When unvaccinated PLWH were evaluated, it was observed that women were less vaccinated than male patients (p=0.01). In PLWH, 145 (89.0%) of patients were vaccinated with single dose, 129 (79.1%) of patients with double dose, and 123 (75.5%) of patients with full dose; in the control group, 145 (89.0%) of patients with single dose, 131 (80.9%) of patients with double dose and 126 (77.3%) of patients with full dose were vaccinated. There was no difference between the groups in the preference of inactivated and mRNA vaccines (p=1.0). Before vaccination, 42 (12.9%) patients were infected. Twenty (12.3%) of these patients were in PLWH group, while 22 (13.5%) patients were in the control group. There were 28 (9.8%) patients who had COVID-19 during or after vaccination, and 10 (6.9%) of them were in PLWH group; 18 (12.4%) of them were in the control group.Conclusion: In our study, no difference was found in the vaccination status, vaccine preference, vaccination doses and COVID-19 history between two groups.
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来源期刊
Acta Medica Mediterranea
Acta Medica Mediterranea 医学-医学:内科
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6-12 weeks
期刊介绍: Acta Medica Mediterranea is an indipendent, international, English-language, peer-reviewed journal, online and open-access, designed for internists and phisicians. The journal publishes a variety of manuscript types, including review articles, original research, case reports and letters to the editor.
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