含脂质体的聚n -异丙基丙烯酰胺低温凝胶的制备、表征及其对色氨酸的吸附性能

IF 0.6 4区工程技术 Q4 CHEMISTRY, MULTIDISCIPLINARY Solvent Extraction Research and Development, Japan Pub Date : 2018-01-01 DOI:10.15261/SERDJ.25.37

Yui Hiramure, Keishi Suga, H. Umakoshi, Jin Matsumoto, K. Shiomori

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引用次数: 3

摘要

在低温冷冻条件下聚合制备了含脂质体的聚n -异丙基丙烯酰胺(PNIPA)冷冻液。该低温凝胶具有孔径20 ~ 30 μm的高孔隙结构。含脂质体的低温凝胶的壁厚大于不含脂质体的低温凝胶。观察了脂质体在低温凝胶中的结构变化和聚集。证实了磷脂的固定化和脂膜在低温凝胶中的动态特性。含脂质体的低温凝胶对l -色氨酸具有手性识别能力。采用含脂质体的PNIPA低温凝胶对l -色氨酸进行了选择性吸附。

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Preparation and Characterization of Poly-N-isopropylacrylamide Cryogels containing Liposomes and Their Adsorption Properties of Tryptophan

Poly-N-isopropylacrylamide (PNIPA) cryogels containing liposomes were prepared by polymerization under freezing conditions at sub-zero temperature. The cryogel had a highly porous structure with 20–30 μm pore size. The wall thickness of the cryogel containing liposomes was larger than that without liposomes. The structural change and aggregation of the liposomes in the cryogel were observed. The immobilization of the phospholipid and the dynamic property of the lipid membrane in the cryogel were confirmed. The cryogel containing liposomes showed chiral recognition ability toward L-Trp. The selective adsorption of L-Trp was achieved with the PNIPA cryogel containing liposome.

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来源期刊

Solvent Extraction Research and Development, Japan 工程技术-工程：化工

CiteScore

1.30

自引率

14.30%

发文量

审稿时长

1 months

期刊介绍： Solvent Extraction Research and Development, Japan (Solvent Extr. Res. Dev., Jpn.) is a periodical issued from Japan Association of Solvent Extraction (JASE) containing papers dealing with all aspects of solvent extraction and their related methods, underlying principles, and materials. Original articles, notes, technical reports, and critical reviews will be considered for publication. Original articles must be of reasonably broad scope and significance to the solvent extraction. Notes will originally describe novel work of a limited nature or especially significant work in progress. Authors can contribute some information of novel techniques, equipment or apparatus, reagents and diluents for solvent extraction as technical reports. Critical reviews will be received from the authors to whom the editorial committee asked to contribute.