农业工人的接触性过敏

M. Kieć-Świerczyńska, B. Kręcisz, D. Świerczyńska-Machura
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引用次数: 3

摘要

向诺弗职业医学研究所提交疑似职业病的农业工人(n = 121)接受了皮肤病学和过敏症检查。所有人都用标准的职业和环境过敏原套装进行了斑贴和点刺试验。接触性皮炎60例(49.6%)。在女性中,主要的过敏是对镍、苯扎konium、钯、钴、硫柳汞、香料和秘鲁香脂,而男性最常见的过敏是对铬酸盐、钴、4-苯二胺、香料、船长、甲醛、4-氨基偶氮苯、羊毛醇和肉桂醇。苯氯化汞致过敏反应女性6例,男性2例,工人对新霉素敏感6例。对戊二醛过敏3例,对来醇过敏4例,对氯己定过敏1例,对氯胺过敏1例。3例患者对硫脲有反应,3例对二苯基胍有反应,3例对巯基苯并噻唑有反应。在9名对4-苯二胺敏感的工人中,只有2名工人对n -异丙基- n -4-苯二胺有额外反应。锆(二甲基二硫代氨基甲酸锌)和硫酸铜各致1例农业工人过敏。43例(35.5%)患者被诊断为立即过敏。这类过敏原主要包括草粉、干草粉、小麦脱粒、黑麦花粉和奶牛上皮。最终的诊断是基于临床表现和贴片和点刺试验的结果。变应性接触性皮炎27例(22.3%),特应性皮炎27例,刺激性接触性皮炎15例(12.4%),荨麻疹9例(7.5%)。其他皮肤疾病均在单个患者中诊断。31例(25.6%)患者临床检查未见皮肤病变。
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Contact Allergy in Agricultural Workers
Agricultural workers (n = 121) referred to the Nofer Institute of Occupational Medicine for suspected occupational disease were subjected to dermatological and allergological examinations. All were patch and prick tested with standard occupational and environmental allergen sets. Contact dermatitis was diagnosed in 60 (49.6%) patients. In the women, the dominant allergy was that to nickel, benzalkonium, palladium, cobalt, thimerosal, fragrances and balsam of Peru, while the men were most frequently sensitive to chromates, cobalt, 4-phenylenediamine, fragrances, captan, formaldehyde, 4-aminoazobenzene, wool alcohols and cinnamic alcohol. Phenylmercuric chloride caused allergic reactions in 6 women and 2 men, while 6 workers were sensitive to neomycin. Allergy to glutaraldehyde was diagnosed in 3 workers, to lysol in 4, to chlorhexidine in 1, to chloramine in 1. Three patients reacted to thiurams, 3 to diphenylguanidine, 3 to mercaptobenzothiazole. Of the 9 workers sensitive to 4-phenylenediamine, only 2 men reacted additionally to N-isopropyl-N-4-phenylenediamine. Ziram (zinc dimethyldithiocarbamate) and copper sulfate caused allergy in 1 agricultural worker each. Immediate allergy was diagnosed in 43 (35.5%) patients. The dominant allergens in that category included straw dust, hay dust, wheat threshing, rye pollen and cow epithelium. The final diagnosis was based on the clinical picture and the results of the patch and prick tests. Allergic contact dermatitis was diagnosed in 27 (22.3%), atopic dermatitis in 27, irritant contact dermatitis in 15 (12.4%) and urticaria in 9 (7.5%) agricultural workers. Other dermal diseases were diagnosed in single patients. The clinical examinations showed no dermal lesions in 31 (25.6%) patients.
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Acknowledgement to Referees for Exogenous Dermatology 2004 Contents Vol. 3, 2004 Author Index Vol. 3, 2004 Is There Evidence that Geraniol Causes Allergic Contact Dermatitis? Subject Index Vol. 3, 2004
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