A case of localized feline demodicosis in the ear canals, refractory to a spot-on formulation of 10% imidacloprid and 1% moxidectin, successfully treated with oral fluralaner

: A 13-month-old, intact, male Bengal cat presented with an 8-month history of bilateral earwax accumulation with mild pruritus. Direct microscopy of the earwax showed plenty of live mites, which were morphologically identical to Demodex cati. No other skin lesions were detected on the cat. A spot-on formulation containing 10% imidacloprid and 1% moxidectin was applied on the back 4 times, once every 2 weeks, but the mites did not disappear. Thereafter, a single oral administration of fluralaner (about 41 mg/kg) improved the symptoms, and no mites were detected on direct microscopy 39 days after the administration.