机械心脏瓣膜置换术中颅内出血的处理

IF 12.2 1区 工程技术 Q1 MECHANICS Applied Mechanics Reviews Pub Date : 2023-05-11 DOI:10.3390/applmech4020033
Sahar Khan, Faiz Syed, Milan Toma
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引用次数: 1

摘要

对接受抗凝治疗的颅内出血患者的处理是医学专业人员面临的一个重大挑战。抗凝治疗的目的是防止血液凝固,但它会加重活动性脑出血。尽管存在这种风险,但避免机械性心脏瓣膜引起的血栓前状态仍然至关重要。目前缺乏处理这一问题的指南,促使人们对胚胎发育和心脏瓣膜的解剖功能、患病瓣膜的瓣膜置换治疗以及抗凝血剂的需求进行深入研究。最后,最近的文献和病例讨论了如何最好地处理机械心脏瓣膜患者的颅内出血。期望这项研究将为机械心脏瓣膜患者颅内出血的处理提供有价值的观点,并刺激这一复杂领域的进一步研究,特别是通过应用力学的视角。
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Management of Intracranial Hemorrhage in the Setting of Mechanical Heart Valve Replacement Therapy
The management of an intracranial hemorrhage in patients receiving anticoagulant therapy presents a significant challenge for medical professionals. Anticoagulant treatment is intended to prevent blood clotting, but it can worsen active brain bleeds. Despite this risk, avoiding the prothrombotic state caused by mechanical heart valves remains crucial. Guidelines on managing this issue are currently lacking, prompting a review that delves into embryonic development and anatomical functions of heart valves, valve replacement therapy for diseased valves, and the need for anticoagulants. Ultimately, recent literature and cases inform discussion regarding how best to manage intracranial hemorrhages in patients with mechanical heart valves. The expectation is that this examination will offer valuable perspectives on the handling of intracranial bleeding among individuals with mechanical heart valves and stimulate additional investigations in this intricate domain, particularly through the lens of applied mechanics.
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来源期刊
CiteScore
28.20
自引率
0.70%
发文量
13
审稿时长
>12 weeks
期刊介绍: Applied Mechanics Reviews (AMR) is an international review journal that serves as a premier venue for dissemination of material across all subdisciplines of applied mechanics and engineering science, including fluid and solid mechanics, heat transfer, dynamics and vibration, and applications.AMR provides an archival repository for state-of-the-art and retrospective survey articles and reviews of research areas and curricular developments. The journal invites commentary on research and education policy in different countries. The journal also invites original tutorial and educational material in applied mechanics targeting non-specialist audiences, including undergraduate and K-12 students.
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