结核治疗患者中与(rpob)利福平耐药相关的基因突变发生率

G. Vasudevan, M. Muthuraj, A. Samrot
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引用次数: 0

摘要

结核病(TB)是一种主要由结核分枝杆菌引起的传染病。印度占全球结核病负担的四分之一。耐药结核病破坏了控制工作,而且在资源有限的情况下,人们对其负担知之甚少。耐药结核病是一种基于实验室的诊断,通过使用固体/液体培养进行表型药敏试验或通过线探针测定/基于核酸扩增试剂盒的基因型试验检测耐药性进行诊断。
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PREVALANCE OF GENETIC MUTATION ASSOSIATED WITH (RPOB) RIFAMPICIN RESISTANT AMONG THE TREATED TUBERCULOSIS PATIENTS
Tuberculosis (TB) is an infectious disease caused predominantly by Mycobacterium tuberculosis. India accounts for one fourth of the global TB burden. Drug-resistant tuberculosis (TB) undermines control efforts and its burden is poorly understood in resource-limited settings. Drug resistant TB is a laboratory based diagnosis and is performed either by phenotypic drug susceptibility testing using solid/liquid culture or genotypic testing for detection of resistance by Line Probe Assay/Cartridge based Nucleic Acid Amplification tests.
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