COVID-19疾病、认识和治疗

Choi Youngah, Jin Hyun-Ju, Song Eun-Hyang, Kim Bu-Yeon, Park Shin-Ae
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摘要

西北医院是首尔市直属医院,主要是结核病医院。该医院是首尔市立公立医院,主要为老年人提供住院和门诊治疗,其中许多老年人患有痴呆症,以及无家可归者和残疾人等边缘化人群。从2020年3月2日到2022年5月31日,指定西北医院对需要固定治疗的新冠肺炎患者进行治疗。韩国的新冠肺炎死亡率在0.1%以下,而美国和欧洲等其他国家的死亡率在1%至2%之间。我们认为,这是由于从2020年2月新冠疫情开始实施的隔离制度造成的。COVID-19检测阳性患者免费住院,通常在COVID-19疾病早期(检测后2 - 3天)住院。本文利用2020年3月2日至2022年5月31日期间在西北医院接受治疗的4531例患者病历数据,通过观察患者的临床特征、用药史和治疗药物,分析了新冠肺炎住院患者的疾病模式。我们治疗指南的关键要素是在COVID-19疾病早期血氧饱和度低于94%时使用Veklury (Remdesivir)或Paxlovid,尽管其成本很高。现在,我们在COVID-19确诊后立即为适当的患者免费使用Veklury和Paxlovid。有分析认为,在感染初期,在医院用雷姆德西韦(Remdesivir)治疗,在家庭治疗中早期使用Paxlovid的隔离制度,对降低韩国的死亡率起到了一定的作用。
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COVID-19 diseases, understanding and treatments
Seobuk Hospital is a hospital directly operated by the Seoul Metropolitan Government and has mainly served as a tuberculosis hospital. It is a Seoul city governmental public hospital which primarily provides inpatients and out patients treatment to the elderly, many of them suffering from dementia patients and the marginalized, such as the homeless and the disabled. From March 2nd, 2020, to May 31th, 2022 Seobuk hospital was appointed to treat COVID-19 patients that required stationary treatment. South Korea’s COVID-19 mortality rate has below 0.1% while in other countries such as the United States and in Europe the mortality rate varies between 1 and 2 %. We believe that it is due to the quarantine system which was put in place right from the start of the COVID-19 pandemic in Febuary 2020. Patients testing positive for COVID-19 were hospitalized free of charge and they were hospitalized usually in early period (2 - 3 days after COVID -19 testing) of COVID-19 disease. In this paper we analyzed the disease patterns of patients hospitalized with COVID-19 using the data from the 4,531 patients charts which received treatment in Seobuk hospital between March 2nd, 2020 and May 31st, 2022 by looking at their clinical features and medication history and medications for treatment. The key element of the guideline of our treatment was to administer Veklury (Remdesivir) or Paxlovid despite its high cost in the early period of the COVID-19 disease when oxygen saturation dropped below 94%. Nowadays we administer Veklury and Paxlovid right after COVID-19 is daignosed free of charge for the proper patient. It is believed that the current quarantine system in South Korea which allows patients to be treated with Veklury (Remdesivir) in hospitals at the initial stage of the infection and with an early Paxlovid administration in home treatment has contributed to lowering the death rate in South Korea.
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