Newer and Aggressive Blood Pressure Goals to Treat Hypertension

The benefits of blood pressure (BP) lowering treatment for the prevention of cardiovascular disease are well established. However, aggressive control of BP is controversial, as it leads to a reduction in organ perfusion and function, thereby increasing overall morbidity and mortality. An elusive balance is now being sought between deleterious effects of hypotension and protective autoregulatory mechanism. Here, we perform a systematic review of data and the current status of aggressive control of BP in various clinical settings.