{"title":"儿童非酒精性脂肪肝的心血管风险:最新进展","authors":"S. Baskar, S. Jhaveri, N. Alkhouri","doi":"10.2217/clp.15.26","DOIUrl":null,"url":null,"abstract":"Abstract Nonalcoholic fatty liver disease (NAFLD) is the most common form of pediatric chronic liver disease in developed countries. NAFLD has risen to epidemic proportions paralleling that of childhood obesity. It is becoming increasingly evident that NAFLD is strongly linked with cardiovascular disease (CVD), which is the leading cause of mortality in the adult NAFLD population. It is very important for physicians caring for children being cognizant of the potential role of childhood NAFLD as an independent risk factor for CVD. Childhood is a time period where subclinical CVD can be detected, giving us the potential ability to halt or reverse the disease process. In this review, we discuss recent evidence linking childhood NAFLD to CVD and potential pathogenic links.","PeriodicalId":55252,"journal":{"name":"Clinical Lipidology","volume":"140 1","pages":"351 - 362"},"PeriodicalIF":0.0000,"publicationDate":"2015-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Cardiovascular risk in pediatric nonalcoholic fatty liver disease: recent advances\",\"authors\":\"S. Baskar, S. Jhaveri, N. Alkhouri\",\"doi\":\"10.2217/clp.15.26\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abstract Nonalcoholic fatty liver disease (NAFLD) is the most common form of pediatric chronic liver disease in developed countries. NAFLD has risen to epidemic proportions paralleling that of childhood obesity. It is becoming increasingly evident that NAFLD is strongly linked with cardiovascular disease (CVD), which is the leading cause of mortality in the adult NAFLD population. It is very important for physicians caring for children being cognizant of the potential role of childhood NAFLD as an independent risk factor for CVD. Childhood is a time period where subclinical CVD can be detected, giving us the potential ability to halt or reverse the disease process. In this review, we discuss recent evidence linking childhood NAFLD to CVD and potential pathogenic links.\",\"PeriodicalId\":55252,\"journal\":{\"name\":\"Clinical Lipidology\",\"volume\":\"140 1\",\"pages\":\"351 - 362\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Lipidology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2217/clp.15.26\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Lipidology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2217/clp.15.26","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q","JCRName":"Medicine","Score":null,"Total":0}
Cardiovascular risk in pediatric nonalcoholic fatty liver disease: recent advances
Abstract Nonalcoholic fatty liver disease (NAFLD) is the most common form of pediatric chronic liver disease in developed countries. NAFLD has risen to epidemic proportions paralleling that of childhood obesity. It is becoming increasingly evident that NAFLD is strongly linked with cardiovascular disease (CVD), which is the leading cause of mortality in the adult NAFLD population. It is very important for physicians caring for children being cognizant of the potential role of childhood NAFLD as an independent risk factor for CVD. Childhood is a time period where subclinical CVD can be detected, giving us the potential ability to halt or reverse the disease process. In this review, we discuss recent evidence linking childhood NAFLD to CVD and potential pathogenic links.
期刊介绍：
The Journal of Clinical Lipidology is published to support the diverse array of medical professionals who work to reduce the incidence of morbidity and mortality from dyslipidemia and associated disorders of lipid metabolism. The Journal''s readership encompasses a broad cross-section of the medical community, including cardiologists, endocrinologists, and primary care physicians, as well as those involved in the treatment of such disorders as diabetes, hypertension, and obesity. The Journal also addresses allied health professionals who treat the patient base described above, such as pharmacists, nurse practitioners and dietitians. Because the scope of clinical lipidology is broad, the topics addressed by the Journal are equally diverse. Typical articles explore lipidology as it is practiced in the treatment setting, recent developments in pharmacological research, reports of treatment and trials, case studies, the impact of lifestyle modification, and similar academic material of interest to the practitioner. While preference is given to material of immediate practical concern, the science that underpins lipidology is forwarded by expert contributors so that evidence-based approaches to reducing cardiovascular and coronary heart disease can be made immediately available to our readers. Sections of the Journal will address pioneering studies and the clinicians who conduct them, case studies, ethical standards and conduct, professional guidance such as ATP and NCEP, editorial commentary, letters from readers, National Lipid Association (NLA) news and upcoming event information, as well as abstracts from the NLA annual scientific sessions and the scientific forums held by its chapters, when appropriate.
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