心血管风险分级模糊系统的多目标优化

Hanna C. Villamil, H. Espitia, L. A. Bejarano
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摘要

由于心血管疾病(cvd)是一个重要的全球关注问题,确定相关的危险因素仍然是关键的研究重点。本研究旨在运用多目标方法提出并优化心血管风险(CVR)分类的模糊系统,解决模糊系统的配置、优化过程、从最优帕累托前沿选择合适解以及优化过程后模糊逻辑系统的可解释性等计算问题。该系统利用包括年龄、体重、身高、性别和收缩压在内的数据来确定心血管风险。模糊模型基于文献中的初步信息;因此,为了使用多目标方法调整模糊逻辑系统,体重指数(BMI)被认为是一个额外的输出,因为该指数有数据可用,并且体重指数被认为是心血管风险的一个代表,因为这些疾病的倾向归因于多余的脂肪组织,这会升高血压、胆固醇和甘油三酯水平,导致动脉和心脏损伤。通过采用多目标方法,本研究旨在获得心血管风险分类和体重指数对应的两个输出之间的平衡。对于多目标优化,提出了一组实验,以获得最优的帕累托前沿,从而确定合适的解决方案。结果表明,模糊逻辑系统得到了充分的优化,在进行优化过程后,模糊集具有可解释性。通过这种方式,本文有助于在医学领域使用计算技术的进步。
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Multiobjective Optimization of Fuzzy System for Cardiovascular Risk Classification
Since cardiovascular diseases (CVDs) pose a critical global concern, identifying associated risk factors remains a pivotal research focus. This study aims to propose and optimize a fuzzy system for cardiovascular risk (CVR) classification using a multiobjective approach, addressing computational aspects such as the configuration of the fuzzy system, the optimization process, the selection of a suitable solution from the optimal Pareto front, and the interpretability of the fuzzy logic system after the optimization process. The proposed system utilizes data, including age, weight, height, gender, and systolic blood pressure to determine cardiovascular risk. The fuzzy model is based on preliminary information from the literature; therefore, to adjust the fuzzy logic system using a multiobjective approach, the body mass index (BMI) is considered as an additional output as data are available for this index, and body mass index is acknowledged as a proxy for cardiovascular risk given the propensity for these diseases attributed to surplus adipose tissue, which can elevate blood pressure, cholesterol, and triglyceride levels, leading to arterial and cardiac damage. By employing a multiobjective approach, the study aims to obtain a balance between the two outputs corresponding to cardiovascular risk classification and body mass index. For the multiobjective optimization, a set of experiments is proposed that render an optimal Pareto front, as a result, to later determine the appropriate solution. The results show an adequate optimization of the fuzzy logic system, allowing the interpretability of the fuzzy sets after carrying out the optimization process. In this way, this paper contributes to the advancement of the use of computational techniques in the medical domain.
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