{"title":"重症恶性疟原虫疟疾相关的噬血细胞淋巴组织细胞增多症1例报告","authors":"Vikram Bhaskar , Shilpa Devamare , Suvasini Sharma , Sunita Sharma , Jagdish Chandra","doi":"10.1016/j.pid.2016.06.011","DOIUrl":null,"url":null,"abstract":"<div><p><span><span>Hemophagocytic lymphohistiocytosis (HLH) has been associated with infections, </span>hematological malignancies<span> and autoimmune conditions. Malaria has been rarely reported as a cause of HLH, and even rarer in pediatric population. We report a case of 10-year-old female child with fever, hepatospenomegaly, </span></span>pancytopenia<span><span>, hyperferritinemia, </span>hypertriglyceridemia<span> and bone marrow hemophagocytosis, favoring the diagnosis of HLH. She required steroid administration for clinical remission.</span></span></p></div>","PeriodicalId":19984,"journal":{"name":"Pediatric Infectious Disease","volume":"8 4","pages":"Pages 115-117"},"PeriodicalIF":0.0000,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.pid.2016.06.011","citationCount":"0","resultStr":"{\"title\":\"Hemophagocytic lymphohistiocytosis associated with severe P. falciparum malaria – A case report\",\"authors\":\"Vikram Bhaskar , Shilpa Devamare , Suvasini Sharma , Sunita Sharma , Jagdish Chandra\",\"doi\":\"10.1016/j.pid.2016.06.011\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p><span><span>Hemophagocytic lymphohistiocytosis (HLH) has been associated with infections, </span>hematological malignancies<span> and autoimmune conditions. Malaria has been rarely reported as a cause of HLH, and even rarer in pediatric population. We report a case of 10-year-old female child with fever, hepatospenomegaly, </span></span>pancytopenia<span><span>, hyperferritinemia, </span>hypertriglyceridemia<span> and bone marrow hemophagocytosis, favoring the diagnosis of HLH. She required steroid administration for clinical remission.</span></span></p></div>\",\"PeriodicalId\":19984,\"journal\":{\"name\":\"Pediatric Infectious Disease\",\"volume\":\"8 4\",\"pages\":\"Pages 115-117\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.pid.2016.06.011\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pediatric Infectious Disease\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2212832816300352\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pediatric Infectious Disease","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2212832816300352","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Hemophagocytic lymphohistiocytosis associated with severe P. falciparum malaria – A case report
Hemophagocytic lymphohistiocytosis (HLH) has been associated with infections, hematological malignancies and autoimmune conditions. Malaria has been rarely reported as a cause of HLH, and even rarer in pediatric population. We report a case of 10-year-old female child with fever, hepatospenomegaly, pancytopenia, hyperferritinemia, hypertriglyceridemia and bone marrow hemophagocytosis, favoring the diagnosis of HLH. She required steroid administration for clinical remission.
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