Visual Analysis of Research Hotspots in Amyotrophic Lateral Sclerosis based on Bibliometrics

Background and objectives: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that is often diagnosed when affected individuals die with respiratory failure. Currently, there are few bibliometrics studies on ALS. Methods: In this study, a comprehensive literature search using the PubMed, WangFang, China National Knowledge Infra-structure, and Chinese Science and Technology Periodical databases was conducted. The Core Collection database for scientific output related to ALS from 1990 to 2022 was also searched. The retrieved dataset was analyzed using. Results: Bibliometrix. A total of 12,450 articles published since 1990 were retrieved, and 243 articles were included in this study. Thirty-two countries contributed to ALS research, among which Italy had the dominant position with the highest number of publications. In addition, keyword co-occurrence was analyzed. As the three indirect subjects of this article, the sources, affili-ations, as well as authors of the study were included in the analysis. Conclusion: