希夫碱金属配合物的合成及其激发清除电位的研究

Khalida F. Al-azawi, Dunya L. AL-Duhaidahawi, A. Al-Amiery, A. Kadhum
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引用次数: 6

摘要

本文引自:Al-Azawi K, AL-Duhaidahawi DL, Al-Amiery A, Kadhum ah。希夫碱金属配合物的合成及其激发清除电位的研究。自由基与抗氧化剂[j] . 2019;9(1):1-4。摘要目的:希夫碱配合物具有碳-氮(N-C)双键,能将电子推入过渡金属中,是一些抗氧化药物的重要替代品。方法:采用MCl2缩合法制备了一系列希夫贱金属配合物。nH2O (M = Co, Ni, Cu)与1-(2羟基苄基氨基)喹啉-2(1H)- 1。结果:希夫碱及其金属配合物通过元素化学分析、摩尔电导、磁化率测量和光谱研究等多种仪器技术进行了表征。对所研究的配合物进行了抗氧化研究。与母体希夫碱和标准化合物相比,所研究的配合物具有良好的抗氧化活性。结论:过渡金属配合物的抗氧化活性明显高于希夫碱。
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Synthesis of Schiff base Metal Complexes with Motivating Scavenging Potential Studies
Cite this article: Al-Azawi K, AL-Duhaidahawi DL, Al-Amiery A, Kadhum AAH. Synthesis of Schiff base Metal Complexes with Motivating Scavenging Potential Studies. Free Radicals and Antioxidants. 2019;9(1):1-4. ABSTRACT Objective: Schiff’s base complexes can be important substitutes for some antioxidant drugs because they have a carbon-nitrogen (N-C) double bond with the ability to push the electrons into the transition metal. Methods: A series of Schiff base metal complexes have been synthesized by the condensation of MCl2.nH2O (M = Co, Ni, Cu) with 1-(2hydroxybenzylideneamino) quinolin-2(1H)-one. Results: The Schiff base and it metal complexes have been characterized by various instrumental techniques like element chemical analysis, molar conductance, magnetic susceptibility measurements and spectral studies. The investigated complexes were subjected to antioxidant studies. The investigated complexes showed an excellent activities as antioxidant as compared to the parent Schiff base and standard compound. Conclusion: The data showed that transition metal complexes have significant improved antioxidant activity than Schiff base.
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