控制核因子κ B活性治疗COVID-19

Pub Date : 2020-05-29 DOI:10.4236/cellbio.2020.92006

M. El-Khodary

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引用次数: 9

摘要

病毒的严重感染会导致细胞因子的过量产生。细胞因子(细胞因子风暴)的过量产生是COVID-19重症病例和死亡的原因。核因子kappa-B刺激负责细胞因子风暴和RNA转录的基因的表达。新冠病毒可通过抑制核因子kappa-B来控制。核因子kappa-B通过抑制过氧化氢和抑制剂kappa-B激酶来控制。

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Treatment of COVID-19 by Controlling the Activity of the Nuclear Factor-Kappa B

Heavy infection of the virus leads to overproduction of cytokines. The overproduction of cytokine (cytokines storms) is responsible for the critical cases and deaths of COVID-19. The nuclear factor kappa-B stimulates the expression of the genes, which is responsible for cytokines storm and RNA transcription. The COVID-19 virus can be controlled by inhibition of nuclear factor kappa-B. Nuclear factor kappa-B is controlled by inhibition of hydrogen peroxide and inhibitor kappa-B kinase enzyme.

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