COVID-19中度感染外周血白细胞特征

A. Yameny
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引用次数: 2

摘要

背景:血液白细胞是人体防御系统的重要组成部分,通过测量白细胞水平可以预测感染状态。COVID-19可能涉及宿主的许多器官系统。研究表明,在SARS-CoV-2疾病期间,血液学特征会发生变化。患者和方法:本研究纳入确诊COVID-19感染的轻度感染患者504例,研究对象随机选取,不分年龄组和性别,采集EDTA血样进行总白细胞和鉴别白细胞检测(Diagon D-cell 60血液分析仪Europe-Diagon Ltd.)。匈牙利)。结果:本组患者年龄14 ~ 75岁,平均年龄44.5±30.5岁,均经实时逆转录聚合酶链反应确诊为新冠肺炎,其中女性(280例,55.6%)多于男性(224例,44.4%)。本研究显示320例患者白细胞总数正常(63.5%),中性粒细胞增多症敏感性77.8%,淋巴细胞减少症敏感性73%。结论:中性粒细胞增多和淋巴细胞减少对COVID-19轻度感染患者(门诊和居家观察患者)诊断或预后的敏感性分别为77.8%和73%。淋巴细胞减少,生物标志物。
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Characteristics of peripheral Leukocyte in moderate infection of COVID-19
: Background: Blood leukocytes are an important part of the body’s defense system, and infection status can be predicted by measuring WBC levels . COVID-19 may involve many organ systems in its host. Studies suggest that hematological profiles change during SARS-CoV-2 illness. Patients and methods: This study included 504 mild infected patients with confirmed COVID-19 infection, these study subjects were randomly selected irrespective of the age group and both genders were included, EDTA blood sample was collected for performing total and differential white blood cells (Diagon D-cell 60 hematology analyzer Europe-Diagon Ltd. Hungary). Results: The present study included patients aged from14 years to 75 years mean age was 44.5 ±30.5 who were confirmed to have Covid-19 based on real-time reverse transcription-polymerase chain reaction, female gender was more frequent (n=280, 55.6%) than Male gender (n=224, 44.4%). This study reveals normal total WBCs count in 320 patients (63.5%), neutrophilia with a sensitivity of 77.8%, and lymphopenia with a sensitivity of 73%. Conclusion: Neutrophilia has a sensitivity of 77.8% and lymphopenia has a sensitivity of 73% for diagnosis or prognosis of mild infection of COVID-19 patients (Outpatients and patients under home observation). lymphopenia, biomarker.
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