{"title":"牛肝和番茄粉对大鼠抗流感莫司抗生素副作用的保护作用","authors":"Naglaa Abd Al-Fattah, Areej Yassin, A. Soliman","doi":"10.21608/bnni.2023.310135","DOIUrl":null,"url":null,"abstract":"his research sought to determine whether interactions between rat diet and the biological and metabolic responses could mitigate the side effects of the antibiotic Flummox. The addition of tomato powder that had been cooked, dried, and ground, along with 10% of lyophilized bovine liver. Out of 44 mature male rats, four main categories were developed. As a negative control, the first set only received regular meals. The third group received lyophilized bovine liver, the fourth group received tomato powder, and the second group received a fundamental diet together with Flumox as a positive control. In comparison to the Flumox group, the liver and tomato-treated groups displayed significantly lower levels of liver enzymes (ALT, AST, and ALP), kidney functions, lymphocytes, leukocytes, and oxidative stress, as well as significantly higher levels of red blood cells hemoglobin and glutathione (GSH) in the hepatic and renal tissues. One can conclude that combining some nutrients (liver, tomato) can reduce the amount of excess weight in rats and treat the many physiological and hematological aberrations caused by oxidative stress diseases connected with antibiotics.","PeriodicalId":9493,"journal":{"name":"Bulletin of the National Nutrition Institute of the Arab Republic of Egypt","volume":"89 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Protective Role of Bovine Liver and Tomato Powder Against Negative Effects of Flummox Antibiotic in Rats\",\"authors\":\"Naglaa Abd Al-Fattah, Areej Yassin, A. Soliman\",\"doi\":\"10.21608/bnni.2023.310135\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"his research sought to determine whether interactions between rat diet and the biological and metabolic responses could mitigate the side effects of the antibiotic Flummox. The addition of tomato powder that had been cooked, dried, and ground, along with 10% of lyophilized bovine liver. Out of 44 mature male rats, four main categories were developed. As a negative control, the first set only received regular meals. The third group received lyophilized bovine liver, the fourth group received tomato powder, and the second group received a fundamental diet together with Flumox as a positive control. In comparison to the Flumox group, the liver and tomato-treated groups displayed significantly lower levels of liver enzymes (ALT, AST, and ALP), kidney functions, lymphocytes, leukocytes, and oxidative stress, as well as significantly higher levels of red blood cells hemoglobin and glutathione (GSH) in the hepatic and renal tissues. One can conclude that combining some nutrients (liver, tomato) can reduce the amount of excess weight in rats and treat the many physiological and hematological aberrations caused by oxidative stress diseases connected with antibiotics.\",\"PeriodicalId\":9493,\"journal\":{\"name\":\"Bulletin of the National Nutrition Institute of the Arab Republic of Egypt\",\"volume\":\"89 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bulletin of the National Nutrition Institute of the Arab Republic of Egypt\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.21608/bnni.2023.310135\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bulletin of the National Nutrition Institute of the Arab Republic of Egypt","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21608/bnni.2023.310135","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Protective Role of Bovine Liver and Tomato Powder Against Negative Effects of Flummox Antibiotic in Rats
his research sought to determine whether interactions between rat diet and the biological and metabolic responses could mitigate the side effects of the antibiotic Flummox. The addition of tomato powder that had been cooked, dried, and ground, along with 10% of lyophilized bovine liver. Out of 44 mature male rats, four main categories were developed. As a negative control, the first set only received regular meals. The third group received lyophilized bovine liver, the fourth group received tomato powder, and the second group received a fundamental diet together with Flumox as a positive control. In comparison to the Flumox group, the liver and tomato-treated groups displayed significantly lower levels of liver enzymes (ALT, AST, and ALP), kidney functions, lymphocytes, leukocytes, and oxidative stress, as well as significantly higher levels of red blood cells hemoglobin and glutathione (GSH) in the hepatic and renal tissues. One can conclude that combining some nutrients (liver, tomato) can reduce the amount of excess weight in rats and treat the many physiological and hematological aberrations caused by oxidative stress diseases connected with antibiotics.