纳米技术在放射治疗计划中的应用范围

S.P. Kishore , N.V.S.L. Narasimham , A. Ramakrishna Prasad
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摘要

本文试图对实体瘤生长数学建模的一些要素进行研究。我们提出了用于描述肿瘤生长的简单的确定性数学模型。通过使用纳米粒子,如金纳米粒子、碳纳米管和磁性纳米粒子,可以使放射治疗非常有效。通过一个例子说明了使用所有必要的生物学假设的模型的发展。多年来,大量的药物输送系统已经被开发出来,以克服癌症治疗中的挑战,从而改善有效性和毒性之间的正确平衡。最后,我们介绍了这些方法的各个方面及其结果。结果表明,在放射治疗计划中使用纳米级粒子具有很大的潜力,可以提高治疗效率。
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Scope of Nanotechnology in Radiation Treatment Planning

In this paper an attempt has been made to study some of the elements of mathematical modeling in solid tumor growth. We present simple deterministic mathematical models used to describe tumor growth. Radiation therapy can be made very effective through the use of nanoscale particles such as gold nanoparticles, carbon nanotubes and magnetic nanoparticles. Development of a model using all the necessary biological assumption has been illustrated through an example. A large number of drug delivery systems have been developed over the years to overcome the challenges in cancer treatment and hence improve the right balance between effectiveness and toxicity. Finally we present various aspects of our methods and their results .The results demonstrate that the use of nanoscale particles in radiation treatment planning holds a lot of potential to improve the efficiency of the treatment.

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