孟加拉国Noakhali市2型糖尿病患者抗糖尿病药物的处方模式

A. Chowdhury, Niloy Sen, Sujan Banik
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引用次数: 10

摘要

本研究的目的是描述孟加拉国Noakhali市2型糖尿病患者抗糖尿病药物处方模式的最新趋势和社会人口学特征。本研究于2016年12月至2017年2月在Noakhali的三家糖尿病医院进行前瞻性横断面研究。本研究采用简单随机方法,共纳入200例门诊患者。在200名受试者中,73.5%的人接受单一治疗,26.5%的人接受多种治疗,其中磺胺脲类常用药物的比例最高(37.5%),但单用二甲双胍(双胍)是口服降糖药中最常见的(28%)药物。最常见的固定剂量组合是磺脲与双胍类药物,以及双胍类药物与糖苷酶抑制剂。高处方胰岛素制剂为胰岛素混合物(11%)。这些药物均使用不同本地或外国公司的传统品牌(100%),15%的处方中至少含有一种复合维生素补充剂。本研究的重点是口服降糖药(OHA)仍占主导地位,但在2型糖尿病的治疗中,有向胰岛素制剂转变的趋势。
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Prescribing pattern of antidiabetic drugs in type 2 diabetic patients of Noakhali city in Bangladesh
The aim of the study was to describe the recent trends in the prescription pattern of antidiabetic drugs and sociodemographic characteristics of type 2 diabetic patients in Noakhali city of Bangladesh. This hospital based prospective, cross-sectional study was carried out in three diabetic hospitals of Noakhali during the period of December, 2016 to February, 2017. A total of 200 outpatients were included in this study by following simple random procedure. Among 200 participants, 73.5% were treated with monotherapy and 26.5% were treated with polytherapy with the highest percentage (37.5%) of commonly prescribed group drugs of sulfonylureas, but lonely metformin (biguanide) was the most commonest (28%) drug among oral hypoglycemic agents. The most accounted fixed dose combination was sulfonylurea with biguanide, and biguanide with glucodiase inhibitors. The highly prescribed insulin preparations was insulin mixtures (11%) among the patients. Drugs were prescribed by traditional brand names (100%) of different local or foreign companies and 15% of prescription were contained at least one multivitamin supplement. It was focused from this study that oral hypoglycemic agents (OHA) yet dominate the prescribing pattern, but there was a shifting trend towards insulin preparation in the management of Type 2 diabetes mellitus.
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