开角型青光眼的超声乳化术及人工晶体植入术。

T. Pohjalainen, E. Vesti, R. Uusitalo, L. Laatikainen
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引用次数: 97

摘要

目的探讨晶状体超声乳化植入术(PHACO IOL)对开角型青光眼(OAG)患者眼压(IOP)及青光眼药物治疗的影响。方法对38例开角型青光眼合并白内障行超声乳化术联合人工晶状体植入术(PHACO IOL)。所有患者均未进行过眼内手术。巩膜切口占37%,角膜透明切口占63%。术后第一天、1周、4个月、29例术后1-3.7年(平均2.8年)复查。结果术前平均IOP为18.4+/-3.3 mmHg,平均1.7种青光眼药物。术后第一天,平均IOP上升至28.2 +/- 12.5 mmHg。39.5%的眼睛眼压低于或等于30 mmHg。一周后,IOP恢复到术前水平。4个月后,IOP进一步下降至16.1 +/- 3.8 mmHg (p = 0.0027)。平均随访1-3.7年(平均2.8年),术后平均IOP为15.1±2.9 mmHg,显著低于术前(p = 0.001), 86%的患者平均使用1.6种药物。切口类型(巩膜或角膜)不影响术后IOP水平。使用Bigger和Becker(1971)的标准,86%的术前控制良好的OAG眼在PHACO-IOL手术后的长期IOP控制得到改善或保持不变,14%的OAG眼的长期IOP控制较差。结论:在OAG眼中,PHACO IOL与IOP显著降低相关,减少用药可达1-3.7年(平均2.8年)。
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Phacoemulsification and intraocular lens implantation in eyes with open-angle glaucoma.
PURPOSE To study the effect of phacoemulsification and intraocular lens implantation (PHACO IOL) on intraocular pressure (IOP) and glaucoma medication in open-angle glaucoma (OAG) eyes. METHODS 38 open-angle glaucoma (OAG) eyes with cataract underwent phacoemulsification and intraocular lens implantation (PHACO IOL) performed by one surgeon (RJU). None of the patients had prior intraocular surgery. Surgery was performed by scleral incision on 37% and by clear corneal incision on 63%. Patients were re-examined on the first postoperative day, after one week, 4 months, and in 29 cases 1-3.7 (mean 2.8) years after the operation. RESULTS The mean preoperative IOP was 18.4+/-3.3 mmHg with a mean of 1.7 glaucoma medications. On the first postoperative day, the mean IOP rose to 28.2 +/- 12.5 mmHg. IOP > or = 30 mmHg occurred in 39.5% of the eyes. After one week, IOP had returned to the preoperative level. After 4 months, IOP had further decreased to 16.1 +/- 3.8 mmHg (p = 0.0027). After a mean follow-up of 1-3.7 (mean 2.8) years, the average postoperative IOP was 15.1 +/- 2.9 mmHg, being significantly (p = 0.001) lower than the preoperative IOP with 86% of the patients having a mean of 1.6 drugs on average. The type of incision (scleral vs. corneal) did not affect the postoperative IOP level. Using the criteria of Bigger and Becker (1971) the long-term IOP control after PHACO-IOL surgery was improved or unchanged in 86% and worse in 14% of the preoperatively well-controlled OAG eyes. CONCLUSIONS In OAG eyes PHACO IOL is associated with a significant decrease in IOP with less medication up to 1-3.7 (mean 2.8) years.
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