印度尼西亚雅加达工人缺血性心脏病的预测措施

Leli Hesti Indriyati, S. GeaPandhita, N. Anis, A. Suraya
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摘要

缺血性心脏病(IHD)是包括印度尼西亚在内的许多国家发病率和死亡率的主要原因之一。因此,在临床实践中需要建立心血管风险预测模型,以便在包括工人在内的高危人群中进行早期发现。本研究旨在开发一种预测风险措施,以早期发现印度尼西亚雅加达的员工中IHD的发病率。数据来源是2019年1月至10月雅加达及周边地区员工和企业家的4100次体检结果数据库。多因素分析显示,年龄>40岁(p=0.000;OR=5.329 (95% CI 2.621-10.833)),有呼吸困难史(p=0.000;OR=5.699 (95% CI 2.524-12.871)),吸烟(p=0.048;OR=2.007 (95% CI 1.924-4.359))和HDL2.5在未来发展为IHD的风险很高。这个计分系统可以被工人或公司用来采取早期预防措施。
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Predictive measure for Ischemic Heart Disease among Workers in Jakarta, Indonesia
Ischemic Heart Disease (IHD) is one of the leading causes of morbidity and mortality in many countries, including Indonesia. Therefore, cardiovascular risk-prediction models are required in clinical practice for early detection in high-risk populations, including the worker population. This study intends to develop a predictive risk measure for early detection of IHD incidences among employees in Jakarta, Indonesia. Source of data was the database of 4,100 medical check-up (MCU) results of employees and entrepreneurs in Jakarta and surrounding areas in January to October 2019. Multivariate analysis showed that being aged >40 years (p=0.000; OR=5.329 (95% CI 2.621-10.833)), having a history of dyspnea (p=0.000; OR=5.699 (95% CI 2.524-12.871)), smoking (p=0.048; OR=2.007 (95% CI 1.924-4.359)) and HDL<50 mg/dL (p=0.049; OR=1.811 (95% CI 1.099-3.281)) were all good predictors to detect IHD in the worker population. The combination of these predictors results with a cut-off point of 2.5, showed accuracy (79.2% sensitivity and 66.3% specificity). Workers who have a score >2.5 are at high risk of developing IHD in the future. This scoring system can be used by workers or companies to take early preventive measures.
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