单峰骆驼(Camelus dromedarius)奶对stz诱导的糖尿病大鼠降糖效果的一致性评价

Sirar A. Baker, Amal M. Al‐Saffar, M. Al-Sughayer
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摘要

糖尿病(DM)是一种异质性代谢紊乱,影响人们生活的任何阶段。在全球范围内,观察到的糖尿病患病率差异很大,但在经常饮用骆驼奶的人群中,糖尿病患病率为零,因为骆驼奶具有很高的营养价值和治疗潜力,可以治疗许多代谢和自身免疫性疾病。本研究通过研究骆驼奶对大鼠的不同降糖作用,并结合相关的生化试验,验证了骆驼奶的功效。雄性Sprague-Dawley大鼠(60mg。Kg-1体重)分别饲喂生的和巴氏消毒的骆驼奶3周,并注射链脲佐菌素诱导糖尿病,同时观察血糖、胆固醇、甘油三酯(TAG)和胰岛素水平。结果表明,生骆驼奶和巴氏消毒骆驼奶的降糖效果都很显著,但生骆驼奶的降糖效果更明显。食用三周的生骆驼奶会显著增加血液中的胆固醇水平,而食用巴氏消毒骆驼奶则会产生相反的效果。两种骆驼奶均显示血液TAG水平显著降低,并经统计学验证。因此,本研究建议,在当前的环境健康问题之后,尤其是糖尿病患者,选择饮用骆驼奶作为免疫增强剂。
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Congruent Assessment of human hypoglycemic effect through STZ-Induced Diabetic rats fed Dromedary Camel (Camelus dromedarius) milk
Diabetes mellitus (DM), a heterogeneous metabolic disorder, affect people at any point of their lives. Globally, a wide variation in the prevalence of diabetes was observed but, showed zero percent within people that regularly consume camel milk because of their highly nutritional and therapeutic potentials to treat many metabolic and autoimmune diseases. The present study validated the efficacy of camel milk by investigating the differential hypoglycemic effects in concurrence with related biochemical tests in rats fed with raw and pasteurized milk of the one-humped Arabian camel (Camelus dromedarius). Male Sprague-Dawley rats (60mg.Kg-1 body weight) fed separately with raw and pasteurized camel milk for three weeks and injected with streptozotocin induced DM besides the investigation on the levels of blood glucose, cholesterol, triacylglycerol (TAG), and insulin. Results showed a significant hypoglycemic effect with both raw and pasteurized camel milk but, more prominent with the raw milk. Three weeks consumption of raw camel milk significantly increased blood cholesterol levels while consumption of pasteurized camel milk caused the reverse. Both types of camel milk revealed significant decrease in the blood TAG levels and were statistically validated. Thus, the present study recommends the choice of camel milk consumption especially in diabetic patients as well, as an immunity booster in the wake of the present environmental health issues.
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来源期刊
Kuwait Journal of Science & Engineering
Kuwait Journal of Science & Engineering MULTIDISCIPLINARY SCIENCES-
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