采用核反应堆生产氟-18的简化程序

Flor de M. Ramirez , Silvia Bulbulian , Carol H. Collins , Kenneth E. Collins
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引用次数: 6

摘要

比较了6Li(n,α)3H反应器生产[18F]氟化物的几种目标化合物和不同纯化工艺;16O(t,n)18F反应序列。以湿润的Li2CO3为目标,然后用阳离子交换树脂水溶液溶解,用稀氢氧化铵作为洗脱液在小氧化铝柱上吸附纯化,得到最佳效果。
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A simplified procedure for fluorine-18 production using a nuclear reactor

Several target compounds and different purification procedures are compared for reactor production of [18F]fluoride by means of the 6Li(n,α)3H; 16O(t,n)18F reaction sequence. Best results are obtained using moist Li2CO3 as target, followed by aqueous dissolution using a cation exchange resin and purification by adsorption on a small alumina column with dilute ammonium hydroxide as eluent.

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