化学和生物抗真菌毒素对黄曲霉中毒期间肉鸡生产性能、血液学、生化和免疫指标的影响

Omnia E. Kilany, Rania Abdou Helmi, I. Fares, Manal A M Mahmoud
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引用次数: 3

摘要

背景:真菌毒素污染饲料是一个世界性的重要问题。真菌毒素是次生毒性真菌代谢物。创造有效的预防和净化方法以减少AFs在畜禽生产中的毒性作用是非常有意义的。目的:评价黄曲霉毒素对仔猪生产性能、血液学、血清生化及免疫学指标的影响,并确定添加抗霉菌毒素的预防作用。方法:选用180只肉鸡,随机分为6组。他们分别给饲喂黄曲霉毒素的肉鸡注射1公斤/吨饲料剂量的zeocem(化学合成抗真菌毒素)和0.25公斤/吨饲料剂量的nutritox(生物合成抗真菌毒素)。所有治疗均在1 ~ 42日龄进行。结果:在试验结束时,生物合成抗真菌毒素nutriitox缓解了黄曲霉毒素对肉鸡生产性能、血清学、血清生化和免疫指标的影响,而化学抗真菌毒素zeocem则缓解了黄曲霉毒素对肉鸡生产性能、血清学、血清生化和免疫指标的影响。结论:生物合成抗真菌毒素(营养毒素)治疗肉鸡黄曲霉中毒效果优于化学合成抗真菌毒素(zeocem)。
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Effects of Chemical and Biological Anti-mycotoxins on Performance, Haematological, Biochemical and Immunological Parameters of Broiler Chickens during Aflatoxicosis
Background:Contamination of feedstuffs with mycotoxins is a worldwide problem of great importance. Mycotoxins are secondary toxic fungal metabolites. There are great interests to create effective prevention and decontamination methods to diminish the toxic effects of AFs in animal and poultry production. Objectives: The present study was designed to evaluate the toxic effects of aflatoxin on performance, some hematological, serum biochemical and immunological parameters and to determine the preventive effect of added anti-mycotoxins. Methods:In this study, a total of 180 broilers were used and divided into 6 equal groups. They received zeocem (chemical synthetic anti-mycotoxin) at a dose of 1 kg/ton feed and nutritox (biological synthetic anti-mycotoxin) at a dose of 0.25 kg/ton feed, to treat broiler fed aflatoxin. All treatments were administered from 1- 42 days of age. Results: By the end of the experiment, nutritox (biological synthetic anti-mycotoxin) alleviated the hazardous effects of aflatoxin on performance, hematological, serum biochemical and immunological parameters rather than zeocem (chemical anti-mycotoxin) fed broilers. Conclusion:Treatment with biological synthetic anti-mycotoxin (nutritox) is better than using chemical synthetic anti-mycotoxin (zeocem) in control of aflatoxicosis in broilers.
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