与宫外孕破裂相关的因素:加纳一家地区医院的10年回顾

IF 1.6 Q3 OBSTETRICS & GYNECOLOGY Obstetrics and Gynecology International Pub Date : 2022-03-07 DOI:10.1155/2022/1491419
Promise E. Sefogah, Nana E Oduro, A. Swarray-Deen, H. G. Nuamah, Raphael B. Takyi, M. Nuamah, S. Oppong
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The confidence interval (CI) was set at 95%, and a p value <0.05 were considered significant. Results Over the ten-year period, there were 115 ectopic pregnancies and 14,450 deliveries (7.9/1,000). The mean age ± standard deviation of the 115 patients was 27.61 ± 5.56. More than half of the patients were single (59/115, 51.3%). The majority (71.3%) of the patients presented with a ruptured ectopic pregnancy. After adjusting for covariates, the odds of an ectopic pregnancy presenting as ruptured among single patients was 2.63 times higher than that of married patients (AOR = 3.63, 95% CI: 1.33–9.93, p=0.01). Ectopic pregnancies located in the isthmic region of the tube had a 77% lower odds of presenting as ruptured than those located in the ampullary region (AOR = 0.23, 95% CI: 0.07–0.74, p=0.01). The odds of rupturing were 1.69 times increased for every additional week after the missed period (AOR = 2.69, 95% CI: 1.56–4.64, p < 0.01). 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引用次数: 2

摘要

背景:大约1-2%的妊娠是异位妊娠。尽管异位妊娠相关的死亡率有所下降,但在撒哈拉以南非洲,与临床表现和结果相关的因素的信息仍然缺乏,这对于确定最适当的治疗方式至关重要。方法:我们对Lekma医院的异位妊娠病例进行了十年的回顾性分析,并评估了其特殊的危险因素、临床表现和结局。患者的社会人口学特征、临床表现和治疗结果之间的关联使用多重逻辑回归进行评估,并以调整优势比(AOR)报告。置信区间(CI)为95%,p值<0.05为显著性。结果10年间宫外孕115例,分娩14450例(7.9/ 1000)。115例患者的平均年龄±标准差为27.61±5.56。超过一半的患者为单身(59/115,51.3%)。大多数(71.3%)患者表现为宫外孕破裂。调整协变量后,单身患者宫外孕破裂的几率是已婚患者的2.63倍(AOR = 3.63, 95% CI: 1.33-9.93, p=0.01)。位于峡部的异位妊娠比位于壶腹区的异位妊娠出现破裂的几率低77% (AOR = 0.23, 95% CI: 0.07-0.74, p=0.01)。漏经后每延长1周,破裂几率增加1.69倍(AOR = 2.69, 95% CI: 1.56 ~ 4.64, p < 0.01)。没有因异位妊娠而死亡的报告。结论异位妊娠以破裂为主。婚姻状况和闭经时间与破裂有显著关系。
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Factors Associated with Ruptured Ectopic Pregnancy: A 10-Year Review at a District Hospital in Ghana
Background Approximately 1–2% of all pregnancies are ectopic. Despite a decline in ectopic pregnancy-related mortality, there is still a paucity of information on the factors associated with clinical presentation and outcomes in Sub-Saharan Africa which is essential in determining the most appropriate treatment modalities. Methods We performed a ten-year retrospective chart review of cases of ectopic pregnancies managed at the Lekma hospital and assessed them for peculiar risk factors, clinical presentation, and outcomes. Associations between patients' sociodemographic characteristics, clinical presentation, and treatment outcome were evaluated using multiple logistic regression and reported as adjusted odds ratios (AOR). The confidence interval (CI) was set at 95%, and a p value <0.05 were considered significant. Results Over the ten-year period, there were 115 ectopic pregnancies and 14,450 deliveries (7.9/1,000). The mean age ± standard deviation of the 115 patients was 27.61 ± 5.56. More than half of the patients were single (59/115, 51.3%). The majority (71.3%) of the patients presented with a ruptured ectopic pregnancy. After adjusting for covariates, the odds of an ectopic pregnancy presenting as ruptured among single patients was 2.63 times higher than that of married patients (AOR = 3.63, 95% CI: 1.33–9.93, p=0.01). Ectopic pregnancies located in the isthmic region of the tube had a 77% lower odds of presenting as ruptured than those located in the ampullary region (AOR = 0.23, 95% CI: 0.07–0.74, p=0.01). The odds of rupturing were 1.69 times increased for every additional week after the missed period (AOR = 2.69, 95% CI: 1.56–4.64, p < 0.01). No mortalities were reported as a result of an ectopic pregnancy. Conclusion Most of the cases of ectopic pregnancy presented ruptured. Marital status and period of amenorrhoea were significantly associated with rupture.
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来源期刊
Obstetrics and Gynecology International
Obstetrics and Gynecology International OBSTETRICS & GYNECOLOGY-
CiteScore
3.60
自引率
0.00%
发文量
26
审稿时长
19 weeks
期刊介绍: Obstetrics and Gynecology International is a peer-reviewed, Open Access journal that aims to provide a forum for scientists and clinical professionals working in obstetrics and gynecology. The journal publishes original research articles, review articles, and clinical studies related to obstetrics, maternal-fetal medicine, general gynecology, gynecologic oncology, uro-gynecology, reproductive medicine and infertility, reproductive endocrinology, and sexual medicine.
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