热疗法作为多学科治疗在直肠癌中的应用:一个新的视角和潜在的作用

H. Shoji, Kazuki Jinbo, K. Sugawara, S. Suda, M. Motegi, H. Murata, K. Ogoshi, Takeo Takahashi, T. Asao, H. Kuwano
{"title":"热疗法作为多学科治疗在直肠癌中的应用:一个新的视角和潜在的作用","authors":"H. Shoji, Kazuki Jinbo, K. Sugawara, S. Suda, M. Motegi, H. Murata, K. Ogoshi, Takeo Takahashi, T. Asao, H. Kuwano","doi":"10.3191/THERMALMED.33.75","DOIUrl":null,"url":null,"abstract":": To avoid colostomy, we try to improve local control, i e . to perform pathological complete response (pCR) by the neoadjuvant chemoradiation (NACR) with concurrent thermal therapy, falling into a so-called “ wait-and-see policy ” . The aim of this study is examined whether the treatment response of NACR with concurrent thermal therapy for rectal cancer can be predicted after the treatment completion and we showed the changing history of our treatment protocol, current results of our study and a new perspective and potential role of thermal therapeutic approaches in patients with rectal cancer. In this study, 81 patients with rectal cancers (54 resected, M : F = 61 : difference RO ≥ 0 Watt group (p < 0.05), but not in the difference RO < 0 Watt group. These data suggest that patients with a small tumor ( GTV ≤ 32 cm 3 ) and a difference RO < 0 Watt are enough to treat by NACR only and those with a large tumor ( GTV ≥ 80 cm 3 ) and a RO difference ≥ 0 Watt by NACR with concurrent with thermal therapy.","PeriodicalId":23299,"journal":{"name":"Thermal Medicine","volume":"27 1","pages":"75-89"},"PeriodicalIF":0.0000,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Thermal Therapy as Multidisciplinary Therapy Applied to Rectal Cancer:: A New Perspective and Potential Role of This Treatment\",\"authors\":\"H. Shoji, Kazuki Jinbo, K. Sugawara, S. Suda, M. Motegi, H. Murata, K. Ogoshi, Takeo Takahashi, T. Asao, H. Kuwano\",\"doi\":\"10.3191/THERMALMED.33.75\",\"DOIUrl\":null,\"url\":null,\"abstract\":\": To avoid colostomy, we try to improve local control, i e . to perform pathological complete response (pCR) by the neoadjuvant chemoradiation (NACR) with concurrent thermal therapy, falling into a so-called “ wait-and-see policy ” . The aim of this study is examined whether the treatment response of NACR with concurrent thermal therapy for rectal cancer can be predicted after the treatment completion and we showed the changing history of our treatment protocol, current results of our study and a new perspective and potential role of thermal therapeutic approaches in patients with rectal cancer. In this study, 81 patients with rectal cancers (54 resected, M : F = 61 : difference RO ≥ 0 Watt group (p < 0.05), but not in the difference RO < 0 Watt group. These data suggest that patients with a small tumor ( GTV ≤ 32 cm 3 ) and a difference RO < 0 Watt are enough to treat by NACR only and those with a large tumor ( GTV ≥ 80 cm 3 ) and a RO difference ≥ 0 Watt by NACR with concurrent with thermal therapy.\",\"PeriodicalId\":23299,\"journal\":{\"name\":\"Thermal Medicine\",\"volume\":\"27 1\",\"pages\":\"75-89\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Thermal Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3191/THERMALMED.33.75\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Thermal Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3191/THERMALMED.33.75","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

为了避免结肠造口,我们尝试改善局部控制,如:通过新辅助放化疗(NACR)同时进行热疗来实现病理完全缓解(pCR),陷入所谓的“观望政策”。本研究的目的是探讨NACR联合热疗在直肠癌治疗完成后的治疗反应是否可以预测,我们展示了我们治疗方案的变化历史、目前的研究结果以及热疗方法在直肠癌患者中的新视角和潜在作用。本研究中81例直肠癌患者(切除54例,M: F = 61例):差异RO≥0瓦特组(p < 0.05),差异RO < 0瓦特组无差异。这些数据表明,小肿瘤(GTV≤32 cm 3)且RO差< 0瓦特的患者仅采用NACR治疗就足够了,大肿瘤(GTV≥80 cm 3)且RO差≥0瓦特的患者采用NACR联合热疗治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Thermal Therapy as Multidisciplinary Therapy Applied to Rectal Cancer:: A New Perspective and Potential Role of This Treatment
: To avoid colostomy, we try to improve local control, i e . to perform pathological complete response (pCR) by the neoadjuvant chemoradiation (NACR) with concurrent thermal therapy, falling into a so-called “ wait-and-see policy ” . The aim of this study is examined whether the treatment response of NACR with concurrent thermal therapy for rectal cancer can be predicted after the treatment completion and we showed the changing history of our treatment protocol, current results of our study and a new perspective and potential role of thermal therapeutic approaches in patients with rectal cancer. In this study, 81 patients with rectal cancers (54 resected, M : F = 61 : difference RO ≥ 0 Watt group (p < 0.05), but not in the difference RO < 0 Watt group. These data suggest that patients with a small tumor ( GTV ≤ 32 cm 3 ) and a difference RO < 0 Watt are enough to treat by NACR only and those with a large tumor ( GTV ≥ 80 cm 3 ) and a RO difference ≥ 0 Watt by NACR with concurrent with thermal therapy.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
前立腺肥大症による中等度から重度の下部尿路症状に対する水蒸気温熱治療の多施設ランダム化偽対照比較試験の最終5年間の結果 低温プラズマおよびハイパーサーミア併用効果を用いたがん治療の可能性 Discovery of Mammalian HSP40 and Subsequent Progress 温度と光を感知し相分離する色素タンパク質フィトクロムB Engineering of Probiotic Bacteria System for the Temperature-sensitive Production of Immune Checkpoint Blockade Nanobodies by Intratumor Heating with Focused Ultrasound
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1