H. Shoji, Kazuki Jinbo, K. Sugawara, S. Suda, M. Motegi, H. Murata, K. Ogoshi, Takeo Takahashi, T. Asao, H. Kuwano
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引用次数: 0
摘要
为了避免结肠造口,我们尝试改善局部控制,如:通过新辅助放化疗(NACR)同时进行热疗来实现病理完全缓解(pCR),陷入所谓的“观望政策”。本研究的目的是探讨NACR联合热疗在直肠癌治疗完成后的治疗反应是否可以预测,我们展示了我们治疗方案的变化历史、目前的研究结果以及热疗方法在直肠癌患者中的新视角和潜在作用。本研究中81例直肠癌患者(切除54例,M: F = 61例):差异RO≥0瓦特组(p < 0.05),差异RO < 0瓦特组无差异。这些数据表明,小肿瘤(GTV≤32 cm 3)且RO差< 0瓦特的患者仅采用NACR治疗就足够了,大肿瘤(GTV≥80 cm 3)且RO差≥0瓦特的患者采用NACR联合热疗治疗。
Thermal Therapy as Multidisciplinary Therapy Applied to Rectal Cancer:: A New Perspective and Potential Role of This Treatment
: To avoid colostomy, we try to improve local control, i e . to perform pathological complete response (pCR) by the neoadjuvant chemoradiation (NACR) with concurrent thermal therapy, falling into a so-called “ wait-and-see policy ” . The aim of this study is examined whether the treatment response of NACR with concurrent thermal therapy for rectal cancer can be predicted after the treatment completion and we showed the changing history of our treatment protocol, current results of our study and a new perspective and potential role of thermal therapeutic approaches in patients with rectal cancer. In this study, 81 patients with rectal cancers (54 resected, M : F = 61 : difference RO ≥ 0 Watt group (p < 0.05), but not in the difference RO < 0 Watt group. These data suggest that patients with a small tumor ( GTV ≤ 32 cm 3 ) and a difference RO < 0 Watt are enough to treat by NACR only and those with a large tumor ( GTV ≥ 80 cm 3 ) and a RO difference ≥ 0 Watt by NACR with concurrent with thermal therapy.