{"title":"单次玻璃体内注射康伯利治疗糖尿病性黄斑水肿的疗效观察","authors":"Xiaopu Yang, Wenzhan Wang, Hao Yao, Dong Zhang","doi":"10.3760/CMA.J.ISSN.2095-1477.2019.11.013","DOIUrl":null,"url":null,"abstract":"Objective \nTo observe the short-term efficacy of single intravitreal injection of conbercept in the treatment of diabetic macular edema (DME). \n \n \nMethods \nThe clinical data of 42 eyes of 37 cases with DME from Oct.2015 to Dec.2017 in Jiaxian County Maternal and Child Health Hospital were analyzed retrospectively.All cases were treated with single intravitreal injection of conbercept. The visual acuity, central macular thickness (CMT) and fluorescein fundus angiography (FFA)before and after injection were analyzed. \n \n \nResults \nVisual acuity was significantly ameliorated at 1 day, 1 and 4 weeks after surgery (P<0.05), and CMT was dramatically reduced (P<0.01). FFA data showed no leakage in 11 eyes, less leakage in 28 eyes and no obvious change in 3 eyes at 4 weeks after treatment. The general effective rate was 92.86%. \n \n \nConclusion \nIntravitreal injection of conbercept improves vision and reduces macular edema in a short period. \n \n \nKey words: \nEdema, macular, diabetic; Conbercept, injection, intravitreal, single time; Efficacy","PeriodicalId":10126,"journal":{"name":"中华眼外伤职业眼病杂志","volume":"37 1","pages":"862-865"},"PeriodicalIF":0.0000,"publicationDate":"2019-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Observation on the efficacy of single intravitreal injection of conbercept for the treatment of diabetic macular edema\",\"authors\":\"Xiaopu Yang, Wenzhan Wang, Hao Yao, Dong Zhang\",\"doi\":\"10.3760/CMA.J.ISSN.2095-1477.2019.11.013\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective \\nTo observe the short-term efficacy of single intravitreal injection of conbercept in the treatment of diabetic macular edema (DME). \\n \\n \\nMethods \\nThe clinical data of 42 eyes of 37 cases with DME from Oct.2015 to Dec.2017 in Jiaxian County Maternal and Child Health Hospital were analyzed retrospectively.All cases were treated with single intravitreal injection of conbercept. The visual acuity, central macular thickness (CMT) and fluorescein fundus angiography (FFA)before and after injection were analyzed. \\n \\n \\nResults \\nVisual acuity was significantly ameliorated at 1 day, 1 and 4 weeks after surgery (P<0.05), and CMT was dramatically reduced (P<0.01). FFA data showed no leakage in 11 eyes, less leakage in 28 eyes and no obvious change in 3 eyes at 4 weeks after treatment. The general effective rate was 92.86%. \\n \\n \\nConclusion \\nIntravitreal injection of conbercept improves vision and reduces macular edema in a short period. \\n \\n \\nKey words: \\nEdema, macular, diabetic; Conbercept, injection, intravitreal, single time; Efficacy\",\"PeriodicalId\":10126,\"journal\":{\"name\":\"中华眼外伤职业眼病杂志\",\"volume\":\"37 1\",\"pages\":\"862-865\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-11-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"中华眼外伤职业眼病杂志\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3760/CMA.J.ISSN.2095-1477.2019.11.013\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华眼外伤职业眼病杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.2095-1477.2019.11.013","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Observation on the efficacy of single intravitreal injection of conbercept for the treatment of diabetic macular edema
Objective
To observe the short-term efficacy of single intravitreal injection of conbercept in the treatment of diabetic macular edema (DME).
Methods
The clinical data of 42 eyes of 37 cases with DME from Oct.2015 to Dec.2017 in Jiaxian County Maternal and Child Health Hospital were analyzed retrospectively.All cases were treated with single intravitreal injection of conbercept. The visual acuity, central macular thickness (CMT) and fluorescein fundus angiography (FFA)before and after injection were analyzed.
Results
Visual acuity was significantly ameliorated at 1 day, 1 and 4 weeks after surgery (P<0.05), and CMT was dramatically reduced (P<0.01). FFA data showed no leakage in 11 eyes, less leakage in 28 eyes and no obvious change in 3 eyes at 4 weeks after treatment. The general effective rate was 92.86%.
Conclusion
Intravitreal injection of conbercept improves vision and reduces macular edema in a short period.
Key words:
Edema, macular, diabetic; Conbercept, injection, intravitreal, single time; Efficacy
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