Non-allergy simple eosinophilic pneumonia—Löffler syndrome

The case of 53-year-old Caucasian woman was presented with 2-month history of low grade fever, shortness of breath, cough and reduced exercise tolerance irreversible to third generation cephalosporins as well as macrolide antimicrobial agents. The diagnosis of simple eosinophilic pneumonia (SEP) (Löffler's syndrome) was confirmed by transbronchial biopsy and by sternal testing. Biopsy specimen of the lung parenchyma showed changes associated with Löffler's syndrome. The diagnosis was, also, confirmed according to radiograph findings of unilateral migratory infiltrates consistent pneumonia. Treatment with corticosteroids resulted in a marked clinical improvement compared to non-corticosteroid therapy.