本研究的目的是评估糖尿病足感染继发性下肢截肢患者的临床特征、微生物分离和并发症。纵向队列研究

Jorge Luis Molina-Valderrama , Alejandro Uribe-Ríos , Damián Martínez-Soto
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引用次数: 0

摘要

背景:85%的糖尿病截肢患者在截肢前出现溃疡。据报道,5年后的再截肢率高达60.7%,重大截肢一年后的死亡率高达69.7%。该研究的目的是表征糖尿病患者的人群,截肢者由于感染相关的糖尿病足在大学医院。材料和方法纳入和排除标准以及社会人口学、临床和微生物学数据收集格式应用于2014年至2016年间所有与糖尿病足相关感染相关的截肢。使用均值和标准差和/或中位数和百分位数。结果患者平均年龄61.6岁。男性和血糖控制不良以及高血压和慢性肾脏疾病等大量合并症占主导地位。24.4%有溃疡,18.1%有截肢。严重截肢占39%。残肢感染占23.6%,再截肢占24.5%。死亡率为4.54%讨论确定代谢控制不良,以及高比例的合并症和并发症。营养随访和血管状态分期不足,对侧足的神经病变、畸形和状态等相关数据报告不足。溃疡和先前截肢的数量很高。有良好的临床/实验室相关性。最初的主要截肢在女性中更为常见。手术部位感染和再截肢的比例很高。证据等级:III
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Descripción del perfil clínico, aislamientos microbiológicos y complicaciones en una población de pacientes con amputación de miembros inferiores secundaria a pie diabético infectado. Estudio de Cohorte Longitudinal

Background

85% of amputations in diabetic patients are preceded by the appearance of an ulcer. Reamputation rates of up to 60.7% at 5 years has been described, as well as mortality of up to 69.7% at one year for major amputations. Aim of the study is to characterize a population of diabetic patients, amputees due to infections associated with diabetic foot in a university hospital.

Material and methods

Inclusion and exclusion criteria and a sociodemographic, clinical and microbiological data collection format were applied to all amputations related to infections associated with diabetic foot between 2014 and 2016. Means and standard deviations and / or medians and percentiles were used.

Results

The average age was 61.6 years. Male sex and poor glycemic control and a high number of comorbidities such as hypertension and chronic kidney disease predominated. 24.4% of previous ulcers and 18.1% previous amputations. Major amputations were 39%. Stump infection was 23.6% and reamputations 24.5%. Mortality was 4.54%

Discussion

Poor metabolic control was identified, as well as a high percentage of comorbidities and complications. Insufficient nutritional follow-up and staging of vascular status with underreporting of relevant data such as neuropathy, deformities and status of the contralateral foot. The number of ulcers and previous amputations was high. There was good clinical / laboratory correlation. Initial major amputations were more frequent in women. There is a high percentage of surgical site infections and reamputations.

Evidence Level: III

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