HIV-1基因组在生物学机制中的作用、分子功能、病毒与宿主细胞组分之间的相互作用、病毒进入机制、染色体整合和转录作为新的预防性HIV-1疫苗开发的潜在靶点

Dr. Zelalem Kiros Bitsue
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摘要

人类免疫缺陷病毒(HIV)基因组共编码三种结构蛋白、两种包膜蛋白、三种酶和六种辅助蛋白。三维分子结构可以提供关于生物机制的详细信息,并且在分子功能影响人类健康的情况下,可以大大有助于制定治疗干预措施。
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The Role of HIV-1 genome on biological mechanisms, Molecular function, Interactions between viral and host cell components, Mechanisms of viral entry, Chromosomal integration, and Transcription as potential target for new Preventive HIV-1 Vaccine Development
The human immunodeficiency virus (HIV) genome encodes a total of three structural proteins, two envelope proteins, three enzymes, and six accessory proteins. Three-dimensional molecular structures can provide detailed information on biological mechanisms and, for cases in which the molecular function affects human health, can significantly aid in the development of therapeutic interventions.
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