{"title":"重复繁殖大鼠生殖周期不同阶段动脉硬化发生的病理生理变化","authors":"Robert F Lutmer , Bernard C Wexler","doi":"10.1016/0010-406X(70)90092-7","DOIUrl":null,"url":null,"abstract":"<div><p></p><ul><li><span>1.</span><span><p>1. Repeatedly bred rats develop arteriosclerosis spontaneously.</p></span></li><li><span>2.</span><span><p>2. Lactation and weaning cause exacerbation of the vascular changes.</p></span></li><li><span>3.</span><span><p>3. Mucopolysaccharides, collagen, elastic tissue and calcific changes are predominant features of the arteriosclerosis.</p></span></li><li><span>4.</span><span><p>4. The adrenal steroids are implicated in conditioning aortic enzyme changes, e.g. beta-glucuronidase, which make for premature arterial disease in breeder rats.</p></span></li></ul></div>","PeriodicalId":78189,"journal":{"name":"Comparative biochemistry and physiology","volume":"37 4","pages":"Pages 445-452, IN1-IN8, 453-466"},"PeriodicalIF":0.0000,"publicationDate":"1970-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0010-406X(70)90092-7","citationCount":"16","resultStr":"{\"title\":\"Pathophysiologic changes associated with the development of arteriosclerosis during various phases of the reproductive cycles of repeatedly bred rats\",\"authors\":\"Robert F Lutmer , Bernard C Wexler\",\"doi\":\"10.1016/0010-406X(70)90092-7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p></p><ul><li><span>1.</span><span><p>1. Repeatedly bred rats develop arteriosclerosis spontaneously.</p></span></li><li><span>2.</span><span><p>2. Lactation and weaning cause exacerbation of the vascular changes.</p></span></li><li><span>3.</span><span><p>3. Mucopolysaccharides, collagen, elastic tissue and calcific changes are predominant features of the arteriosclerosis.</p></span></li><li><span>4.</span><span><p>4. The adrenal steroids are implicated in conditioning aortic enzyme changes, e.g. beta-glucuronidase, which make for premature arterial disease in breeder rats.</p></span></li></ul></div>\",\"PeriodicalId\":78189,\"journal\":{\"name\":\"Comparative biochemistry and physiology\",\"volume\":\"37 4\",\"pages\":\"Pages 445-452, IN1-IN8, 453-466\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1970-12-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/0010-406X(70)90092-7\",\"citationCount\":\"16\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Comparative biochemistry and physiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/0010406X70900927\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Comparative biochemistry and physiology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0010406X70900927","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
2. Lactation and weaning cause exacerbation of the vascular changes.
3.
3. Mucopolysaccharides, collagen, elastic tissue and calcific changes are predominant features of the arteriosclerosis.
4.
4. The adrenal steroids are implicated in conditioning aortic enzyme changes, e.g. beta-glucuronidase, which make for premature arterial disease in breeder rats.
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