为什么抗微生物药物耐药性也是一个兽医问题?

E. Mateu, M. Martín
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引用次数: 55

摘要

抗微生物药物耐药性已成为世界范围内公共卫生战略的主要问题之一。人们对肠球菌或沙门氏菌等致病性微生物的出现给予了很大的关注,这些微生物已经形成了耐药性机制,使它们几乎无法用目前的抗生素治疗。据称出现这种情况的原因之一是抗生素的非医疗使用,特别是对动物的使用。然而,直到最近才有兽医论坛和期刊开始讨论这个话题。另一方面,抗微生物药物耐药性也已成为兽医学中的一个问题,表明动物源性微生物的高耐药率的报告数量相当可观。本综述涉及常见兽医使用抗生素的已知耐药性机制,兽药中的抗微生物耐药性问题以及动物抗生素使用与人类抗微生物耐药性出现之间的联系。
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Why is anti-microbial resistance a veterinary problem as well?
Resistance to anti-microbial agents has become one of the main issues in public health strategies world-wide. Much attention has been paid to the emergence of pathogenic micro-organisms such as enterococci or Salmonella that have developed resistance mechanisms that render them almost untreatable with current antibiotics. One of the alleged reasons for such an emergence is the non-medical use of antibiotics, especially in animals. However, only recently have veterinary forums and journals begun to discuss this topic. On the other hand, anti-microbial resistance has also become a problem in veterinary medicine and the number of reports indicating high rates of resistance among animal-originated micro-organisms is considerable. The present review deals with the mechanisms of resistance known for antibiotics in common veterinary use, the problem of anti-microbial resistance in veterinary medicine and the links between the use of antibiotics in animals and the emergence of anti-microbial resistance in humans.
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