干细胞及其在中枢神经系统损伤治疗中的应用

Majid Hassanpourezatti, Zahra Nikookar
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摘要

1. 2.脊髓损伤细胞组织疗法大脑和脊髓损伤最常见的原因是事故、跌倒、运动损伤和创伤,这些都会导致感觉和运动功能障碍。在利用干细胞修复和预防中枢神经系统损伤引起的并发症的发展方面已经做出了巨大的努力。该领域的主要挑战是选择合适的干细胞来替代丢失的神经细胞,并防止破坏干细胞功能的过程。本文综述了近年来各种干细胞在神经系统损伤治疗中的研究进展,并对其功能的可能机制进行了讨论。此外,根据基础研究和临床研究的结果,描述了干细胞治疗的优缺点。干细胞治疗的高成本和不良副作用是使用干细胞治疗修复神经系统的主要挑战。因此,需要更多的研究来优化临床环境中的细胞治疗方法。结论:不同类型、不同能力的干细胞的存在,解决存在的问题,可以增加利用干细胞治疗神经系统损伤的希望。m摘要文章简介:
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Stem Cells and their Applications for the Treatment of Injuries to the Central Nervous System
1. Spinal Cord Injuries 2. Celland Tissue-Based Therapy 3. Stem Cells Introduction: The most common causes of brain and spinal cord injuries are accidents, falls, sports injuries, and trauma, which can lead to sensory and motor function deficits. Enormous efforts have been made to use stem cells to repair and prevent the development of complications caused by damage to the central nervous system. The main challenge in this field is to select the right stem cells to replace the lost nerve cells and prevent processes that disrupt the function of stem cells. In this review article, current information on various stem cells used in the treatment of damage to the nervous system, the possible mechanisms of their functions have been discussed. Furthermore, advantages and disadvantages of stem cell therapy are described based on the findings of basic and clinical studies. The high cost of stem cell therapy and unwanted side effects are major challenges in using stem cell therapy to repair the nervous system. Thus, more investigations are required to optimize cell therapy approaches in clinical settings. Conclusion: The existence of different types of stem cells with diverse capabilities and solving existing problems can increase the hope of using of stem cell therapy to treat damage to the nervous system.m ABSTRACT Article Info:
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