某地区癌症中心姑息治疗病房剧痛及其治疗分析

P. Kannan, K. Gunaseelan, Parthasarathy
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摘要

目的:疼痛是困扰癌症患者最常见的症状之一,影响了患者满意的生活质量。在全球范围内,近80%的癌症患者很少或没有接受止痛药治疗,癌症疼痛几乎没有得到控制。本研究是为了分析疼痛的患病率和疼痛治疗的病人提出姑息治疗单位在区域癌症中心。方法:对我院姑息治疗中心2142例患者的姑息治疗登记及随访表进行分析,了解患者的人口学资料、治疗特点,确定我院区域癌症中心癌症患者的疼痛患病率、严重程度及治疗情况。结果:近50%的癌症患者有头颈部和胃肠道恶性肿瘤,只接受了最好的支持治疗。在40%的患者中发现了IV期疾病,骨骼转移(52%)最为常见。该研究显示,我们中心的癌症疼痛患病率为92.4%。约40%的疼痛患者在首次到姑息治疗单位就诊时,疼痛评分为7-10分。大约65%的严重疼痛患者在初次登记后的姑息治疗单位的第一次随访中对吗啡治疗有反应。在平均十个月的随访中,患者每次就诊的平均总体疼痛评分从7分左右下降到4分。结果意义:因此,癌症患者疼痛发生率高,严重疼痛患者很少或根本没有接受阿片类药物治疗,这可能是由于对初级肿瘤科医生和住院医师缺乏足够的关于强阿片类药物处方的教育和培训。这种审计可能有助于修改现有政策和制定姑息治疗的新政策。
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Analysis of Severe Pain and its Treatment in a Palliative Care Unit in a Regional Cancer Centre
Objective : Pain is one of the most common symptoms that troubles cancer patients and precludes satisfactory quality of life. Globally, nearly 80% of the cancer patients receive little or no pain medication and cancer pain is barely controlled. This study was done to analyse the prevalence of pain and pain treatment in patients presenting to palliative care unit in a regional cancer centre. Methods : Palliative care registry and follow-up forms of 2142 patients who got registered in our palliative care unit were analysed to obtain the demographic details, treatment characteristics and to determine the prevalence of pain, its severity, and treatment in cancer patients in our regional cancer centre. Results : Nearly 50% of the cancer population had head and neck and gastrointestinal tract malignancies and received only best supportive care. Stage IV disease was found in 40% of patients, and skeletal metastasis (52%) was most common. This study showed a 92.4% prevalence of cancer pain in our centre. About 40% of patients with pain had a pain score of 7-10 by Numerical rating scale on initial presentation to the palliative care unit. About 65% of the patients with severe pain had a response to treatment withmorphine during their first follow-up to palliative care unit after initial registration. The average overall pain score of the patients per visit decreased from around 7 to 4 at a median follow-up of ten months. Significance of results : Thus, there is a high prevalence of pain in cancer patients and patients with severe pain receive little or no opioid medication at all probably due to the lack of adequate education and training to the primary oncologists and residents regarding prescription of strong opioids. This audit may help in the modification of existing and formulation of new policies in the delivery of palliative care.
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