儿童耐发性急腹症与Covid-19 1例报告

N. Amenzoui, K. Gharib, S. Kalouche, A. Chlilek, F. Ailal, A. Bousfiha
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引用次数: 0

摘要

严重急性呼吸系统综合征冠状病毒-2 (SARS-CoV-2)是一种全球性的大流行疾病,通常表现为传染性肺炎,部分患者也出现胃肠道和肝脏表现。了解新冠肺炎患者胃肠道病变的临床特点及可能的致病机制,制定治疗策略。因此,我们报告了一名与covid - 19阳性患者直接接触的女孩,她的急性发热消化图片显示她感染了covid - 19。当资产负债表上的PCR covid呈阴性和血清学covid 19 (IgM阳性和IgG阳性)呈白色时,进行手术探查。总之,我们正在慢慢开始了解SARS-CoV-2感染的复杂发病机制。COVID-19广泛存在的器官特异性并发症,包括胃肠道并发症,现在越来越受到重视。对这种多器官疾病的胃肠道损害和临床表现的彻底了解仍然是必要的。严重急性呼吸综合征冠状病毒2型(SARS CoV 2)是一种全球性大流行疾病,主要表现为呼吸道症状。已观察到越来越多与COVID-19相关的肺外症状和表现,包括胃肠道(GI)和肝脏表现。很少有成人病例系列报告急性腹部是SARS-COV-2感染的症状我们的工作目标是向处理Covid-19疑似病例的医生提供有关急性腹部事件的最新信息。病例报告这是一名9岁的女校长,没有明显的既往病史,与两周前感染covid阳性的母亲有直接接触,因急腹症合并休克入院。病史可追溯到入院前一周,发热超过39°C, 3天后并发弥漫性急性腹痛,伴水样腹泻和餐后呕吐,无相关呼吸道症状。该患儿最初在小儿休克复苏时入院,临床检查时她昏睡,格拉斯哥12/15,发热39°C,毛细血管再充盈时间超过3秒,心动过速160次/分钟,呼吸急促至53次/分钟,室内空气氧饱和度96%,血压80 / 60mg,触诊伴有腹肌挛缩的严重腹痛,无肝或脾肿大。调理后,进行腹部超声检查,显示低生理性,有利于中等丰度的腹腔内液体积液。面对这一临床放射图像,怀疑腹膜炎,但紧急进行手术探查,结果不明显。生物学上,我们注意到存在高crp,高铁蛋白血症,淋巴细胞减少,以及血小板减少。表1给出了更多的细节。表1。患者血液学及生化特征检测结果参考区间CRP 316 mg/l 0.0-5.0铁蛋白1200 /mm3 15-200尿素1.05 g/l 0.13-0.43肌酐26 mg/l 5.7-11.1
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Intriguing Acute Abdomen and Covid-19 in children : A case report
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is a worldwide pandemic, manifested commomly by infectious pneumonia, some patients also develop gastrointestinal (GI) and hepatic manifestations. To understand the clinical features and possible pathogenic mechanisms leading to gastrointestinal lesions in COVID-19 to formulate therapeutic strategy. Thus, we report the case of a girl with an acute febrile digestive picture revealing COVID19 infection, having direct contact with a COVIDpositive person. Surgical exploration was performed when white, on the balance sheet a PCR covid was negative and serology covid 19 (IgM positive and IgG positive). In conclusion, we are slowly starting to understand the complex pathogenesis of SARS-CoV-2 infections. The widespread organospecific complications of COVID-19, including those of the gastrointestinal system, are now increasingly appreciated. A thorough understanding of the gastrointestinal damage and clinical manifestations of this multi-organ disease remains imperative. Introduction Severe acute respiratory syndrome coronavirus 2 (SARS CoV 2) is a global pandemic, manifested mainly by respiratory symptoms. An increasing number of extra-pulmonary symptoms and manifestations linked to COVID-19 have been observed, including gastrointestinal (GI) and hepatic manifestations. Very few adult case series have reported acute abdomen as a symptom of SARS-COV-2 infection.1 The objective of our work is to update physicians working with suspected cases of the Covid-19 on acute abdominal events. Case Report This is a 9-year-old head girl, with no significant past medical history, having direct contact with his mother who was covid positive two weeks before, admitted for an acute abdomen with shock. The history of the disease dates back to a week before its admission with fever over 39° C, complicated three days later by diffuse acute abdominal pain associated with watery diarrhea and vomiting post meals, without associated respiratory symptoms. The child was initially admitted in pediatric resuscitation in shock, on clinical examination she was drowsy with Glasgow 12/15, febrile at 39° C, capillary refill time above 3 seconds, tachycardia of 160 beats per minute, polypnea to 53 cycles per minute, 96% oxygen saturation in room air, blood pressure at 80 / 60mmg, severe abdominal pain generalized on palpation associated with contracture of the abdominal muscles, without hepatomegaly or splenomegaly. After the conditioning, an abdominal ultrasound was performed and showed a hypoecogenic ledure in favour of an intraperitoneal fluid effusion of medium abundance. Faced with this clinico-radiological picture, peritonitis was suspected but the surgical exploration carried out urgently, came back unremarkable. Biologically, we note the presence of a high crp, high ferritinémia, lymphopenia, as well as thrombocytopenia. More details are given in Table 1. Table 1. Hematological and Biochemical profile of the our patient Test Results Reference interval CRP 316 mg/l 0.0-5.0 Ferritin 1200 /mm3 15-200 Urea 1.05 g/l 0.13-0.43 Creatinine 26 mg/l 5.7-11.1
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