{"title":"99Tc-HMPAO非对映异构体稀水溶液的稳定性","authors":"Hueisch Jy Ding, Si Jung Yeh","doi":"10.1016/0883-2889(92)90220-9","DOIUrl":null,"url":null,"abstract":"<div><p>A series of dilute solutions of <sup>99</sup>Tc-HMPAO/<sup>99 + 99m</sup>Tc-HMPAO diastereoisomers whose concentrations ranged from 10<sup>−8</sup> to 10<sup>−4</sup> M were prepared and the rates of decrease in <sup>99</sup>Tc-HMPAO diastereoisomers were determined. For the concentration ranges between 10<sup>−8</sup> and 10<sup>−4</sup> M the rates of decrease in their concentration were measured by ITLC and paper chromatography (three strips method). Ultraviolet and visible spectrophotometry was used to determine the rates of concentration changes for 10<sup>−6</sup> ∼ 10<sup>−4</sup> M solutions. The results were compared with previous work.</p></div>","PeriodicalId":14288,"journal":{"name":"International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1992-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0883-2889(92)90220-9","citationCount":"4","resultStr":"{\"title\":\"Stability of dilute aqueous solutions of 99Tc-HMPAO diastereoisomers\",\"authors\":\"Hueisch Jy Ding, Si Jung Yeh\",\"doi\":\"10.1016/0883-2889(92)90220-9\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>A series of dilute solutions of <sup>99</sup>Tc-HMPAO/<sup>99 + 99m</sup>Tc-HMPAO diastereoisomers whose concentrations ranged from 10<sup>−8</sup> to 10<sup>−4</sup> M were prepared and the rates of decrease in <sup>99</sup>Tc-HMPAO diastereoisomers were determined. For the concentration ranges between 10<sup>−8</sup> and 10<sup>−4</sup> M the rates of decrease in their concentration were measured by ITLC and paper chromatography (three strips method). Ultraviolet and visible spectrophotometry was used to determine the rates of concentration changes for 10<sup>−6</sup> ∼ 10<sup>−4</sup> M solutions. The results were compared with previous work.</p></div>\",\"PeriodicalId\":14288,\"journal\":{\"name\":\"International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1992-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/0883-2889(92)90220-9\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/0883288992902209\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0883288992902209","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Stability of dilute aqueous solutions of 99Tc-HMPAO diastereoisomers
A series of dilute solutions of 99Tc-HMPAO/99 + 99mTc-HMPAO diastereoisomers whose concentrations ranged from 10−8 to 10−4 M were prepared and the rates of decrease in 99Tc-HMPAO diastereoisomers were determined. For the concentration ranges between 10−8 and 10−4 M the rates of decrease in their concentration were measured by ITLC and paper chromatography (three strips method). Ultraviolet and visible spectrophotometry was used to determine the rates of concentration changes for 10−6 ∼ 10−4 M solutions. The results were compared with previous work.
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