E. Yunir, Beta Agustia Wisman, Dono Antono, A. Mansjoer, Angela Sarumpaet, Eni Iswati, Martha Rosana, D. Tahapary, T. Tarigan, P. Soewondo
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引用次数: 1
摘要
背景:慢性肢体缺血(CLI)与糖尿病患者死亡率增加密切相关。目的:本研究的目的是评估影响CLI患者血管内血管重建术后1年内死亡率的因素。方法:本回顾性队列研究基于印度尼西亚雅加达三级医院Cipto Mangunkusumo国立综合医院心血管综合中心的医疗记录。该研究包括2008年1月至2018年6月期间接受血管内血运重建术的199例伴有2型糖尿病(T2DM)的CLI患者。血管内血运重建术后随访1年。采用Kaplan-Meier和Cox比例风险分析对数据进行分析。结果1年生存率为58.8%。Cox比例风险分析显示，糖尿病持续时间(HR 3.52;95% CI 1.34-9.22)，贫血(HR 2.59;95% CI 1.47-4.56)和吸烟(HR 2.49;95% CI 1.46-4.27)与血管内血运重建术后1年内的死亡率显著相关。结论:在伴有CLI的T2DM患者中，糖尿病病程、贫血和吸烟与血管内血运重建术后1年内较高的死亡风险相关
Factors Affecting Mortality of Critical Limb Ischemia 1 Year after Endovascular Revascularization in Patients with Type 2 Diabetes Mellitus
BACKGROUND Chronic limb ischemia (CLI) is strongly associated with increased mortality in diabetes patients. OBJECTIVE The aim of this study was to evaluate factors affecting mortality within 1 year after endovascular revascularization in CLI patients. METHODS This retrospective cohort study was based on medical records from the Integrated Cardiovascular Centre of Dr. Cipto Mangunkusumo National General Hospital, a tertiary care hospital in Jakarta, Indonesia. The study included 199 CLI patients with type 2 diabetes mellitus (T2DM) who underwent endovascular revascularization from January 2008 to June 2018. The patients were followed up for 1 year after endovascular revascularization. Kaplan-Meier and Cox proportional hazard analysis was used to analyze the data. RESULTS 1-year survival probability was 58.8%. Cox proportional hazard analysis showed that duration of diabetes (HR 3.52; 95% CI 1.34-9.22), anemia (HR 2.59; 95% CI 1.47-4.56), and smoking (HR 2.49; 95% CI 1.46-4.27) were significantly associated with mortality within 1 year after endovascular revascularization. CONCLUSIONS In T2DM patients with CLI, duration of diabetes, anemia and smoking were associated with a higher risk of mortality within 1 year post endovascular revascularization
期刊介绍：
The Review of Diabetic Studies (RDS) is the society"s peer-reviewed journal published quarterly. The purpose of The RDS is to support and encourage research in biomedical diabetes-related science including areas such as endocrinology, immunology, epidemiology, genetics, cell-based research, developmental research, bioengineering and disease management.
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