在实验性哮喘模型中，雌激素放大了先前存在的特应性相关Th2偏倚

Clinical & Experimental Allergy Pub Date : 2019-11-30 DOI:10.1111/cea.13544

J. Lauzon-Joset, K. T. Mincham, A. Abad, B. Short, P. Holt, D. Strickland, J. Leffler

{"title":"在实验性哮喘模型中，雌激素放大了先前存在的特应性相关Th2偏倚","authors":"J. Lauzon-Joset, K. T. Mincham, A. Abad, B. Short, P. Holt, D. Strickland, J. Leffler","doi":"10.1111/cea.13544","DOIUrl":null,"url":null,"abstract":"The prevalence and severity of asthma, particularly the most common (atopic) form of the disease, increase amongst females but not males after puberty, and asthma activity also changes throughout the menstrual cycle and during pregnancy. The contribution of female sex hormones to asthma pathogenesis is incompletely understood.","PeriodicalId":10148,"journal":{"name":"Clinical & Experimental Allergy","volume":"8 1","pages":"391 - 400"},"PeriodicalIF":0.0000,"publicationDate":"2019-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"14","resultStr":"{\"title\":\"Oestrogen amplifies pre‐existing atopy‐associated Th2 bias in an experimental asthma model\",\"authors\":\"J. Lauzon-Joset, K. T. Mincham, A. Abad, B. Short, P. Holt, D. Strickland, J. Leffler\",\"doi\":\"10.1111/cea.13544\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The prevalence and severity of asthma, particularly the most common (atopic) form of the disease, increase amongst females but not males after puberty, and asthma activity also changes throughout the menstrual cycle and during pregnancy. The contribution of female sex hormones to asthma pathogenesis is incompletely understood.\",\"PeriodicalId\":10148,\"journal\":{\"name\":\"Clinical & Experimental Allergy\",\"volume\":\"8 1\",\"pages\":\"391 - 400\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-11-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"14\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical & Experimental Allergy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1111/cea.13544\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical & Experimental Allergy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1111/cea.13544","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 14

摘要

青春期后，哮喘的患病率和严重程度，特别是最常见的(特应性)形式的哮喘，在女性中增加，而在男性中没有增加，哮喘活动在整个月经周期和怀孕期间也会发生变化。女性性激素在哮喘发病中的作用尚不完全清楚。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

Oestrogen amplifies pre‐existing atopy‐associated Th2 bias in an experimental asthma model

The prevalence and severity of asthma, particularly the most common (atopic) form of the disease, increase amongst females but not males after puberty, and asthma activity also changes throughout the menstrual cycle and during pregnancy. The contribution of female sex hormones to asthma pathogenesis is incompletely understood.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Clinical & Experimental Allergy

自引率

0.00%

发文量